This book uniquely relates the broad impact of signal transduction research on the understanding and treatment of human disease. There have been significant advances in the area of signaling in disease processes, yet no resource presently connects these advances with understanding of disease processes and applications for novel therapeutics. Given the emphasis on translational research and biological relevance in biotechnology, and, conversely, the importance of molecular approaches for clinical research, it is evident that a single resource bridging signaling research and human disease will be invaluable.
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"...appropriate for a textbook...pathways and their regulation are well explained and there are helpful tables and illustrations. The information is current and is well referenced...Finkel, Gutkind, and their coauthors have put together examples that illustrate the growing depth of understanding the roles of signal transduction in disease..."
Cell, January 9, 2004
Cell, January 9, 2004