Biomedical Materials and Diagnostic Devices (eBook, ePUB)

Redaktion: Tiwari; Turner, Anthony P. F.; Kobayashi, Hisatoshi; Ramalingam, Murugan

• Format: ePub

Produktbeschreibung

Biomedical Materials and Diagnostics Devices provides an up-to-date overview of the fascinating and emerging field of biomedical materials and devices, fabrication, performance, and uses The biomedical materials with the most promising potential combine biocompatibility with the ability to adjust precisely the biological phenomena in a controlled manner. The world market for biomedical and diagnostic devices is expanding rapidly and the pace of academic research resulted in about 50,000 published papers in recent years. It is timely, therefore, to assemble a volume on this important subject. The chapters in the book seek to address progress in successful design strategies for biomedical materials and devices such as the use of collagen, crystalline calcium orthophosphates, amphiphilic polymers, polycaprolactone, biomimetic assembly, bio-nanocomposite matrices, bio-silica, theranostic nanobiomaterials, intelligent drug delivery systems, elastomeric nanobiomaterials, electrospun nano-matrices, metal nanoparticles, and a variety of biosensors. This large and comprehensive volume includes twenty chapters authored by some of the leading researchers in the field, and is divided into four main areas: biomedical materials; diagnostic devices; drug delivery and therapeutics; and tissue engineering and organ regeneration.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 640
• Erscheinungstermin: 16. Oktober 2012
• Englisch
• ISBN-13: 9781118522936
• Artikelnr.: 37344209

Autorenporträt

Ashutosh Tiwari is an assistant professor of nanobioelectronics at Biosensors and Bioelectronics Centre, IFM-Linköping University, Sweden, as well as Editor-in-Chief of Advanced Materials Letters. He has published more than 125 articles and patents as well as authored/edited books in the field of materials science and technology. Murugan Ramalingam is an associate professor of biomaterials and tissue engineering at the Institut National de la Santé et de la Recherche Médicale, Université de Strasbourg (UdS), France. Concurrently, he holds an adjunct associate professorship at Tohoku University, Japan. He has authored more than 125 publications and is Editor-in-Chief of Journal of Bionanoscience and Journal of Biomaterials and Tissue Engineering. Hisatoshi Kobayashi is group leader of Biofunctional Materials at Biomaterials Centre, National Institute for Materials Science, Japan. He has published more than 150 publications, books and patents in the field of biomaterials science and technology, as well as edited/authored three books on the advanced state-of-the-art of biomaterials. Professor Anthony P. F. Turner is currently Head of Division, FM-Linköping University's new Centre for Biosensors and Bioelectronics. His previous thirty-five-year academic career in the United Kingdom culminated in the positions of Principal (Rector) of Cranfield University and Distinguished Professor of Biotechnology. Professor Turner has more than 600 publications and patents in the field of biosensors and biomimetic sensors and is best known for his role in the development of glucose sensors for home-use by people with diabetes. He published the first textbook on Biosensors in 1987 and is Editor-In-Chief of the principal journal in his field, Biosensors & Bioelectronics, which he cofounded in 1985.

Inhaltsangabe

Preface xv Part I: Biomedical Materials 1. Application of the Collagen as
Biomaterials 3 Kwangwoo Nam and Akio Kishida 1.1 Introduction 3 1.2
Structural Aspect of Native Tissue 5 1.3 Processing of Collagen Matrix 8
1.4 Conclusions and Future Perspectives 14 2. Biological and Medical
Significance of Nanodimensional and Nanocrystalline Calcium Orthophosphates
19 Sergey V. Dorozhkin 2.1 Introduction 19 2.2 General Information on
?Nano? 21 2.3 Micron- and Submicron-Sized Calcium Orthophosphates versus
the Nanodimensional Ones 23 2.4 Nanodimensional and Nanocrystalline Calcium
Orthophosphates in Calcified Tissues of Mammals 26 2.5 The Structure of the
Nanodimensional and Nanocrystalline Apatites 28 2.6 Synthesis of the
Nanodimensional and Nanocrystalline Calcium Orthophosphates 34 2.7
Biomedical Applications of the Nanodimensional and Nanocrystalline Calcium
Orthophosphates 47 2.8 Other Applications of the Nanodimensional and
Nanocrystalline Calcium Orthophosphates 58 2.9 Summary and Perspectives 58
2.10 Conclusions 61 3. Layer-by-Layer (LbL) Thin Film: From Conventional To
Advanced Biomedical and Bioanalytical Applications 101 Wing Cheung MAK 3.1
State-of-the-art LbL Technology 101 3.2 Principle of Biomaterials Based Lbl
Architecture 102 3.3 LbL Thin Film for Biomaterials and Biomedical
Implantations 103 3.4 LbL Thin Film for Biosensors and Bioassays 105 3.5
LbL Thin Film Architecture on Colloidal Materials 107 3.6 LbL Thin Film for
Drug Encapsulation and Delivery 108 3.7 LbL Thin Film Based
Micro/Nanoreactor 110 4. Polycaprolactone based Nanobiomaterials 115
Narendra K. Singh and Pralay Maiti 4.1 Introduction 115 4.2 Preparation of
Polycaprolactone Nanocomposites 118 4.3 Characterization of
Poly(caprolactone) Nanocomposites 119 4.4 Properties 123 4.5
Biocompatibility and Drug Delivery Application 141 4.6 Conclusion 150
Acknowledgement 150 5. Bone Substitute Materials in Trauma and Orthopedic
Surgery ? Properties and Use in Clinic 157 Esther M.M. Van Lieshout 5.1
Introduction 158 5.2 Types of Bone Grafts 159 5.3 Bone Substitute Materials
161 5.4 Combinations with Osteogenic and Osteoinductive Materials 171 5.5
Discussion and Conclusion 173 6. Surface Functionalized Hydrogel
Nanoparticles 191 Mehrdad Hamidi, Hajar Ashrafi and Amir Azadi 6.1 Hydrogel
Nanoparticles 191 6.2 Hydrogel Nanoparticles Based on Chitosan 193 6.3
Hydrogel Nanoparticles Based on Alginate 194 6.4 Hydrogel Nanoparticles
Based on Poly(vinyl Alcohol) 195 6.5 Hydrogel Nanoparticles Based on
Poly(ethylene Oxide) and Poly(ethyleneimine) 196 6.6 Hydrogel Nanoparticles
Based on Poly(vinyl Pyrrolidone) 198 6.7 Hydrogel Nanoparticles Based on
Poly-N-Isopropylacrylamide 198 6.8 Smart Hydrogel Nanoparticles 199 6.9
Self-assembled Hydrogel Nanoparticles 200 6.10 Surface Functionalization
201 6.11 Surface Functionalized Hydrogel Nanoparticles 205 Part II:
Diagnostic Devices 7. Utility and Potential Application of Nanomaterials in
Medicine 215 Ravindra P. Singh, Jeong -Woo Choi, Ashutosh Tiwari and
Avinash Chand Pandey 7.1 Introduction 215 7.2 Nanoparticle Coatings 218 7.3
Cyclic Peptides 220 7.4 Dendrimers 221 7.5 Fullerenes/Carbon
Nanotubes/Graphene 227 7.6 Functional Drug Carriers 229 7.7 MRI Scanning
Nanoparticles 233 7.8 Nanoemulsions 235 7.9 Nanofibers 236 7.10 Nanoshells
239 7.11 Quantum Dots 240 7.12 Nanoimaging 248 7.13 Inorganic Nanoparticles
248 7.14 Conclusion 250 8. Gold Nanoparticle-based Electrochemical
Biosensors for Medical Applications 261 Ülkü Anik 8.1 Introduction 261 8.2
Electrochemical Biosensors 262 8.3 Conclusion 272 9. Impedimetric DNA
Sensing Employing Nanomaterials 277 Manel del Valle and Alessandra Bonanni
9.1 Introduction 277 9.2 Electrochemical Impedance Spectroscopy for
Genosensing 280 9.3 Nanostructured Carbon Used in Impedimetric Genosensors
286 9.4 Nanostructured Gold Used in Impedimetric Genosensors 290 9.5
Quantum Dots for Impedimetric Genosensing 293 9.6 Impedimetric Genosensors
for Point-of-Care Diagnosis 293 9.7 Conclusions (Past, Present and Future
Perspectives) 294 10. Bionanocomposite Matrices in Electrochemical
Biosensors 301 Ashutosh Tiwari, Atul Tiwari 10.1 Introduction 301 10.2
Fabricationof SiO2-CHIT/CNTs Bionanocomposites 303 10.3 Preparation of
Bioelectrodes 304 10.4 Characterizations 305 10.5 Electrocatalytic
Properties 307 10.6 Photometric Response 315 10.7 Conclusions 316 11.
Biosilica? Nanocomposites - Nanobiomaterials for Biomedical Engineering and
Sensing Applications 321 Nikos Chaniotakis, Raluca Buiculescu 11.1
Introduction 321 11.2 Silica Polymerization Process 323 11.3 Biocatalytic
Formation of Silica 325 11.4 Biosilica Nanotechnology 327 11.5 Applications
328 11.6 Conclusions 334 12. Molecularly Imprinted Nanomaterial-based
Highly Sensitive and Selective Medical Devices 337 Bhim Bali Prasad and
Mahavir Prasad Tiwari 12.1 Introduction 337 12.2 Molecular Imprinted
Polymer Technology 340 12.3 Molecularly Imprinted Nanomaterials 360 12.4
Molecularly Imprinted Nanomaterial-based Sensing Devices 362 12.5
Conclusion 379 13. Immunosensors for Diagnosis of Cardiac Injury 391
Swapneel R. Deshpande, Aswathi Anto Antony, Ashutosh Tiwari, Emilia
Wiechec, Ulf Dahlström, Anthony P.F. Turner 13.1 Immunosensor 391 13.2
Myocardial Infarction and Cardiac Biomarkers 392 13.3 Immunosensors for
Troponin 399 13.4 Conclusions 404 Part III: Drug Delivery and Therapeutics
14. Ground-Breaking Changes in Mimetic and Novel Nanostructured Composites
for Intelligent-, Adaptive- and In vivo-responsive Drug Delivery Therapies
411 Dipak K. Sarker 14. 1 Introduction 411 14.2 Obstacles to the Clinician
420 14.3 Hurdles for the Pharmaceuticist 428 14.4 Nanostructures 431 14.5
Surface Coating 435 14.7 Formulation Conditions and Parameters 439 14.8
Delivery Systems 440 14.9 Evaluation 443 14.10 Conclusions 447 15. Progress
of Nanobiomaterials for Theranostic Systems 451 Dipendra Gyawali, Michael
Palmer, Richard T. Tran and Jian Yang 15.1 Introduction 451 15.2 Design
Concerns for Theranostic Nanosystems 456 15.3 Designing a Smart and
Functional Theranostic System 459 15.4 Materials for Theranostic System 462
15.5 Theranostic Systems and Applications 474 15.6 Future Outlook 481 16.
Intelligent Drug Delivery Systems for Cancer Therapy 493 Mousa Jafari,
Bahram Zargar, M. Soltani, D. Nedra Karunaratne, Brian Ingalls, P. Chen
16.1 Introduction 493 16.2 Peptides for Nucleic Acid and Drug Delivery in
Cancer Therapy 494 16.3 Lipid Carriers 499 16.4 Polymeric Carriers 506 16.5
Bactria Mediated Cancer Therapy 514 16.6 Conclusion 519 Part IV: Tissue
Engineering and Organ Regeneration 531 17. The Evolution of Abdominal Wall
Reconstruction and the Role of Nonobiotecnology in the Development of
Intelligent Abdominal Wall Mesh 533 Cherif Boutros, Hany F. Sobhi and Nader
Hanna 17.1 The Complex Structure of the Abdominal Wall 534 17.2 Need for
Abdominal Wall Reconstruction 535 17.3 Failure of Primary Repair 535 17.4
Limitations of the Synthetic Meshes 536 17.5 Introduction of Biomaterials
To Overcome Synthetic Mesh Limitations 537 17.6 Ideal Material for
Abdominal Wall Reconstruction 538 17.7 Role of Bionanotechnology in
Providing the 17.7 Future Directions 542 18. Poly(Polyol Sebacate)-based
Elastomeric Nanobiomaterials for Soft Tissue Engineering 545 Qizhi Chen
18.1 Introduction 545 18.2 Poly(polyol sebacate) Elastomers 547 18.3
Elastomeric Nanocomposites 562 18.4 Summary 569 19. Electrospun Nanomatrix
for Tissue Regeneration 577 Debasish Mondal and Ashutosh Tiwari 19.1
Introduction 577 19.2 Electrosun Nanomatrix 578 19.3 Polymeric Nanomatrices
for Tissue Engineering 580 19.4 Biocompatibility of the Nanomatrix 581 19.5
Electrospun Nanomatrices for Tissue Engineering 583 19.6 Status and
Prognosis 592 20. Conducting Polymer Composites for Tissue Engineering
Scaffolds 597 Yashpal Sharma, Ashutosh Tiwari and Hisatoshi Kobayashi 20.1
Introduction 598 20.3 Synthesis of Conducting Polymers 599 20.4 Application
of Conducting Polymer in Tissue Engineering 600 20.5 Polypyrrole 600 20.6
Poly(3,4-ethylene dioxythiophene) 602 20.7 Polyaniline 603 20.8 Carbon
Nanotube 605 20.9 Future Prospects and Conclusions 607 21. Cell Patterning
Technologies for Tissue Engineering 611 Azadeh Seidi and Murugan Ramalingam
21.1 Introduction 611 21.2 Patterned Co-culture Techniques 612 21.3
Applications of Co-cultures in Tissue Engineering 618 21.4 Concluding
Remarks 619 Acknowledgements 619 References 620 Index 000