Pairet

COX-2 Inhibitors

Herausgegeben:Pairet, Michel; Ryn, Joanne van

• Gebundenes Buch

Produktbeschreibung

COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.

Produktdetails

• Milestones in Drug Therapy
• Verlag: Birkhäuser / Birkhäuser Basel / Springer, Basel
• Artikelnr. des Verlages: 10888125, 978-3-7643-6901-9
• 2004
• Seitenzahl: 264
• Erscheinungstermin: 29. März 2004
• Englisch
• Abmessung: 241mm x 160mm x 20mm
• Gewicht: 724g
• ISBN-13: 9783764369019
• ISBN-10: 3764369019
• Artikelnr.: 12275083

Inhaltsangabe

The discovery of COX-2.- Structural diversity of selective COX-2 inhibitors.- The molecular and biological basis for COX-2 selectivity.- Pharmacology and toxicology of COX-2 inhibitors.- Efficacy and gastrointestinal safety of selective COX-2 inhibitors.- Role of COX-2 in ulcers and ulcer healing.- COX-2 and the cardiovascular system.- Effects on the kidney: role of COX-2 inhibitors.- Effects on the lungs: role of COX-2 inhibitors.- Reproduction: role of COX-2 and its inhibition.- COX-2 in cancer.