Parasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system. This book examines current knowledge about immune responses to parasitic infections affecting humans, including interactions that occur during co-infections, and how immune responses may be manipulated to develop therapeutic interventions against parasitic infection. For easy reference, the…mehr
Parasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system. This book examines current knowledge about immune responses to parasitic infections affecting humans, including interactions that occur during co-infections, and how immune responses may be manipulated to develop therapeutic interventions against parasitic infection.
For easy reference, the most commonly studied parasites are examined in individual chapters written by investigators at the forefront of their field. An overview of the immune system, as well as introductions to protozoan and helminth parasites, is included to guide background reading. A historical perspective of the field of immunoparasitology acknowledges the contributions of investigators who have been instrumental in developing this field of research.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Tracey Lamb is the editor of Immunity to Parasitic Infection, published by Wiley.
Inhaltsangabe
List of Contributors xiii Introduction: Immunoparasitology: The Making of a Modern Immunological science 1 Alan Sher Section 1 1 Notes on the Immune System 15 Tracey J. Lamb References for further reading 54 Section 2 2 Introduction to Protozoan Infections 61 David B. Guiliano and Tracey J. Lamb References for further reading 88 3 Apicomplexa:Malaria 91 Tracey J. Lamb and Francis M. Ndung'u References for further reading 105 4 Apicomplexa: Toxoplasma gondii 107 EmmaWilson References for further reading 118 5 Apicomplexa: Cryptosporidium 121 Jan R. Mead andMichael J. Arrowood References for further reading 134 6 Diplomonadida: Giardia 139 Steven Singer References for further reading 150 7 Kinetoplastids: Leishmania 153 IngridM uller and Pascale Kropf References for further reading 164 8 Kinetoplastids: Trypanosomes 165 Jeremy Sternberg References for further reading 176 9 Kinetoplastids: Trypanosoma cruzi (Chagas disease) 179 Rick Tarleton References for further reading 189 Section 3 10 Introduction to Helminth Infections 195 David B. Guiliano References for further reading 213 11 Nematoda: Filarial Nematodes 217 Sabine Specht and Achim Hoerauf References for further reading 229 12 Nematoda: Ascaris lumbricoides 231 Christina Dold References for further reading 243 13 Nematoda: Hookworms 247 Soraya Gaze, HenryMcSorley and Alex Loukas References for further reading 259 14 Nematoda: Trichuris 263 Colby Zaph References for further reading 271 15 Nematoda: Trichinella 275 Judith A. Appleton, Lisa K. Blum and Nebiat G. Gebreselassie References for further reading 284 16 Trematoda: Schistosomes 287 Mark Wilson References for further reading 303 17 Cestoda: Tapeworm Infection 307 C esar A. Terrazas,Miriam Rodr ?guez-Sosa and Luis I. Terrazas References for further reading 320 Section 4 18 Co-infection: Immunological Considerations 325 Joanne Lello References for further reading 333 19 HIV and Malaria Co-infection 335 Aubrey Cunnington and EleanorM. Riley References for further reading 351 20 HIV and Leishmania Co-infection 353 JavierMoreno References for further reading 359 21 Gastrointestinal Nematodes and Malaria 361 Mathieu Nacher References for further reading 372 22 Malaria and Schistosomes 375 ShonaWilson and Jamal Khalife References for further reading 385 Section 5 23 Hygiene and Other Early Childhood Influences on the Subsequent Function of the Immune System 391 Graham A.W. Rook References for further reading 400 24 Nematodes as Therapeutic Organisms 401 William Harnett andMargaretM. Harnett References for further reading 413 AlbertoMoreno References for further reading 429 Yasuyuki Goto and Steven G. Reed References for further reading 438 Brent Schneider,Maria Victoria Periago and Jeffrey M. Bethony References for further reading 456 Sara Lustigman References for further reading 468 Abbreviations 471 Glossary 479 Index 493
List of Contributors xiii Introduction: Immunoparasitology: The Making of a Modern Immunological science 1 Alan Sher Section 1 1 Notes on the Immune System 15 Tracey J. Lamb References for further reading 54 Section 2 2 Introduction to Protozoan Infections 61 David B. Guiliano and Tracey J. Lamb References for further reading 88 3 Apicomplexa:Malaria 91 Tracey J. Lamb and Francis M. Ndung'u References for further reading 105 4 Apicomplexa: Toxoplasma gondii 107 EmmaWilson References for further reading 118 5 Apicomplexa: Cryptosporidium 121 Jan R. Mead andMichael J. Arrowood References for further reading 134 6 Diplomonadida: Giardia 139 Steven Singer References for further reading 150 7 Kinetoplastids: Leishmania 153 IngridM uller and Pascale Kropf References for further reading 164 8 Kinetoplastids: Trypanosomes 165 Jeremy Sternberg References for further reading 176 9 Kinetoplastids: Trypanosoma cruzi (Chagas disease) 179 Rick Tarleton References for further reading 189 Section 3 10 Introduction to Helminth Infections 195 David B. Guiliano References for further reading 213 11 Nematoda: Filarial Nematodes 217 Sabine Specht and Achim Hoerauf References for further reading 229 12 Nematoda: Ascaris lumbricoides 231 Christina Dold References for further reading 243 13 Nematoda: Hookworms 247 Soraya Gaze, HenryMcSorley and Alex Loukas References for further reading 259 14 Nematoda: Trichuris 263 Colby Zaph References for further reading 271 15 Nematoda: Trichinella 275 Judith A. Appleton, Lisa K. Blum and Nebiat G. Gebreselassie References for further reading 284 16 Trematoda: Schistosomes 287 Mark Wilson References for further reading 303 17 Cestoda: Tapeworm Infection 307 C esar A. Terrazas,Miriam Rodr ?guez-Sosa and Luis I. Terrazas References for further reading 320 Section 4 18 Co-infection: Immunological Considerations 325 Joanne Lello References for further reading 333 19 HIV and Malaria Co-infection 335 Aubrey Cunnington and EleanorM. Riley References for further reading 351 20 HIV and Leishmania Co-infection 353 JavierMoreno References for further reading 359 21 Gastrointestinal Nematodes and Malaria 361 Mathieu Nacher References for further reading 372 22 Malaria and Schistosomes 375 ShonaWilson and Jamal Khalife References for further reading 385 Section 5 23 Hygiene and Other Early Childhood Influences on the Subsequent Function of the Immune System 391 Graham A.W. Rook References for further reading 400 24 Nematodes as Therapeutic Organisms 401 William Harnett andMargaretM. Harnett References for further reading 413 AlbertoMoreno References for further reading 429 Yasuyuki Goto and Steven G. Reed References for further reading 438 Brent Schneider,Maria Victoria Periago and Jeffrey M. Bethony References for further reading 456 Sara Lustigman References for further reading 468 Abbreviations 471 Glossary 479 Index 493
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