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This monograph covers the entire field of blood group serology, with its main emphasis on the chemical and biochemical basis of blood group specificity. Full consideration is given to molecular biology investigations, in particular to studies on the structure of blood group genes and the molecular biological basis of alleles and rare blood group variants, whereby relevant literature up to the year 2000 is covered. The text is supplemented by numerous illustrations and tables, and detailed reference lists. The five years since the publication of the first edition have brought further advances…mehr

Produktbeschreibung
This monograph covers the entire field of blood group serology, with its main emphasis on the chemical and biochemical basis of blood group specificity. Full consideration is given to molecular biology investigations, in particular to studies on the structure of blood group genes and the molecular biological basis of alleles and rare blood group variants, whereby relevant literature up to the year 2000 is covered. The text is supplemented by numerous illustrations and tables, and detailed reference lists. The five years since the publication of the first edition have brought further advances in blood group research. Thanks to modern molecular biology, scientists have not only been able to identify the bearer molecules of many more blood groups, they have clarified the molecular basis of a number of further blood group specifities as well. This book offers a concise survey for use by blood bankers and researchers in biochemistry, blood group serology, immunohematology, forensic medicine, population genetics, and anthropology.
  • Produktdetails
  • SpringerMedizin
  • Verlag: Springer-Verlag GmbH / Springer-Verlag KG
  • Artikelnr. des Verlages: 10764127
  • 2., kompl. überarbeitete Auflage. Revised
  • Erscheinungstermin: 26. Juni 2000
  • Englisch
  • Abmessung: 241mm x 158mm x 48mm
  • Gewicht: 1085g
  • ISBN-13: 9783211834718
  • ISBN-10: 3211834710
  • Artikelnr.: 06108544
Inhaltsangabe
INHALT LANG: Introduction Glycoconjugates Glycolipids
Glycoproteins Biosynthesis of Glycoconjugates Biosynthesis of Glycoproteins
Biosynthesis of Glycosphingoliopids
Regulation of Chain Structure Erythrocyte Membrane Constituents of the Erythrocyte Membrane
Molecular Architecture of the Erythrocyte Membrane
Architecture of the Membranes of Nucleated Cells ABO(H) System Genetics
Antisera and Lectins
Blood Group ABH Substances
Biosynthesis of ABH Antigens and its Genetic Regulation
ABH Subgroups and Variants Lewis System and the Antigens Lex and Ley Genetics
Antisera and Lectins
Blood Group Lewis Substances
Biosynthesis of Blood Group Lewis Determinants
Antigens Lex and Ley Antigens I and i Antisera
Blood Group I and i Determinants
Blood Group I and i Substances
Expression of I and i Activity During Embryonic Development and under Various Pathological Conditions
Biosynthesis of I and i Determinant Structures P System Antisera and Lectins
Blood Group P Substances
Biosynthesis of the Blood Group P Antigens MNS System Genetics
Antisera and Lectins
Blood Group MNS Substances
Structure and Organisation of the MNS Gene Complex
Chemical Structures of the Main Determinants of the MNS System
Rare Variants of the MNS Antigens
MNS-Deficient Phenotypes, and Antigens Associated with MNS System Polyagglutination Antisera and Lectins
T Antigen
Tk Antigen
Th Antigen
Tx Antigen
Tn Antigen
VA and NOR Sid and Cad Antisera and Lectins
Sda Active Substances
Cad Active Substances
Investigations on the Biosynthesis of Sda and Cad Determinants Slalic Acid-Containing Receptors for Cold Agglutinins Antisera
Structures of Antigenic Determinants
Occurrence of Pr, Gd, and Sa Antigens on Other Cell Types
Other Receptors for Cold Agglutinins Rh System Genetics
Rh Antisera, Chemical Properties of Rh Antigens
Number of Rh Proteins
Molecular Biological Investigations
Rh Antigens and Phenotypes Landsteiner-Wiener System Chido / Rodgers System Duffy System Kell System Antibodies
Kell-Deficient Phenotypes
Kell Glycoprotein
Kell Alleles
Kx Antigen Gerbich System Glycophorin C and Glycophorin D
The Antigen Characters Ge1, Ge2, Ge3, and Ge4, and the Lsa Determinant
Wb (Webb)
Dha (Duch)
Ana (Ahonen) Lutheran System Diego System Antibodies
The Antigens of the Diego System Cromer System Dombrock System Yt System Indian System Knops System Kidd System Xg System Colton System OK System JMH Antigen Antigens of the Major Histocompatibilitiy Complex (HLA Antigens) Genetics
HLA Antisera
HLA Gene Products HEMPAS Carcinoembryonic Antigen (CEA) Family

INHALT LANG: Introduction Glycoconjugates Glycolipids; Glycoproteins Biosynthesis of Glycoconjugates Biosynthesis of Glycoproteins; Biosynthesis of Glycosphingoliopids; Regulation of Chain Structure Erythrocyte Membrane Constituents of the Erythrocyte Membrane; Molecular Architecture of the Erythrocyte Membrane; Architecture of the Membranes of Nucleated Cells ABO(H) System Genetics; Antisera and Lectins; Blood Group ABH Substances; Biosynthesis of ABH Antigens and its Genetic Regulation; ABH Subgroups and Variants Lewis System and the Antigens Lex and Ley Genetics; Antisera and Lectins; Blood Group Lewis Substances; Biosynthesis of Blood Group Lewis Determinants; Antigens Lex and Ley Antigens I and i Antisera; Blood Group I and i Determinants; Blood Group I and i Substances; Expression of I and i Activity During Embryonic Development and under Various Pathological Conditions; Biosynthesis of I and i Determinant Structures P System Antisera and Lectins; Blood Group P Substances; Biosynthesis of the Blood Group P Antigens MNS System Genetics; Antisera and Lectins; Blood Group MNS Substances; Structure and Organisation of the MNS Gene Complex; Chemical Structures of the Main Determinants of the MNS System; Rare Variants of the MNS Antigens; MNS-Deficient Phenotypes, and Antigens Associated with MNS System Polyagglutination Antisera and Lectins; T Antigen; Tk Antigen; Th Antigen; Tx Antigen; Tn Antigen; VA and NOR Sid and Cad Antisera and Lectins; Sda Active Substances; Cad Active Substances; Investigations on the Biosynthesis of Sda and Cad Determinants Slalic Acid-Containing Receptors for Cold Agglutinins Antisera; Structures of Antigenic Determinants; Occurrence of Pr, Gd, and Sa Antigens on Other Cell Types; Other Receptors for Cold Agglutinins Rh System Genetics; Rh Antisera, Chemical Properties of Rh Antigens; Number of Rh Proteins; Molecular Biological Investigations; Rh Antigens and Phenotypes Landsteiner-Wiener System Chido / Rodgers System Duffy System Kell System Antibodies; Kell-Deficient Phenotypes; Kell Glycoprotein; Kell Alleles; Kx Antigen Gerbich System Glycophorin C and Glycophorin D; The Antigen Characters Ge1, Ge2, Ge3, and Ge4, and the Lsa Determinant; Wb (Webb); Dha (Duch); Ana (Ahonen) Lutheran System Diego System Antibodies; The Antigens of the Diego System Cromer System Dombrock System Yt System Indian System Knops System Kidd System Xg System Colton System OK System JMH Antigen Antigens of the Major Histocompatibilitiy Complex (HLA Antigens) Genetics; HLA Antisera; HLA Gene Products HEMPAS Carcinoembryonic Antigen (CEA) Family
Rezensionen
"... This book is well organized, accurate ... Helmut Schenkel-Brunner is to be congratulated on compiling and presenting the information in a clear and consice manner ... "Human blood groups: chemical and biochemical basis of antigen specificity" is a useful reference book for the shelf of those interested in understanding the biochemical and genetical aspects of blood group antigens." Human Genetics 2001