KI-Beratung Beta

Produktbild: Kratom

Kratom History, Science and Therapeutic Potential

152,99 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

29.09.2025

Herausgeber

Jack E. Henningfield + weitere

Verlag

Elsevier Science & Technology

Seitenzahl

262

Maße (L/B/H)

23,4/19/1,4 cm

Gewicht

576 g

Sprache

Englisch

ISBN

978-0-443-27412-1

Beschreibung

Portrait

Jack E. Henningfield, PhD, is Vice President, Research, Health Policy, and Abuse Liability at Pinney Associates, and Adjunct Professor, Behavioral Biology, Department of Psychiatry and Behavioral Sciences, at the Johns Hopkins University School of Medicine. His research and contributions to drug regulation and public policy have contributed to the development of medicines and other approaches for behavioral and CNS disorders and improved public health. He focuses on abuse liability and Controlled Substances Act (CSA) scheduling within the CSA Eight Factor Analysis of CNS-active substances. At NIDA, he led abuse potential assessments and developed drug scheduling recommendations in the Intramural Research Program in collaboration with FDA and DEA. He has contributed to comments to FDA on drug regulation and policy, and has written numerous books and monographs, and more than 500 published papers and reports for various governmental agencies and other organizations. His efforts have earned him a multitude of awards.

Chad E. Beyer, PhD, MBA is CEO of Kures, Inc, a clinical-stage company focused on addiction. With more than 25 years of experience, Dr. Beyer is a drug hunter with a successful record of discovering and developing disease-modifying medications. He was formerly CEO and SVP of R&D at Promentis Pharmaceuticals and the Head of Neurochemistry at Wyeth Pharmaceuticals. Dr. Beyer has led numerous preclinical and clinical teams, participated in the submission of 33 INDs, and contributed to the commercialization of two blockbuster medications: Effexor® and Pristiq®. Dr. Beyer holds a Ph.D. in Pharmacology from LSU Medical Center and an MBA from the Rutgers Business School and has served on the Board of Directors of various companies. Notably, Dr. Beyer has authored more than 70 manuscripts, co-edited the book entitled "Next Generation Antidepressants,” co-founded the journal "Technology Transfer & Entrepreneurship,” and is an Entrepreneur in Residence at Lafayette College.

Dr. Raffa is Adjunct Professor at the University of Arizona College of Pharmacy, and Professor Emeritus at Temple University School of Pharmacy, with master's degrees in Biomedical Engineering and Toxicology, and a doctorate in Pharmacology. He was a Research Fellow on the Scientific Ladder and Team Co-Leader for analgesics drug discovery in the CNS Group at Johnson & Johnson. He cofounded CaRafe Drug Innovation and Enalare Therapeutics, serving as the CSO of Neumentum Inc., and Advantx Pharmaceuticals, companies dedicated to developing non-opioid analgesics and treatment of overdoses. He is the co-holder of several patents, some on tramadol plus acetaminophen. He has published over 400 papers and pharmacological books. He is Associate Editor-in-Chief of the Journal of Pain Research, and past president of the Mid-Atlantic Pharmacology Society of ASPET. He lectures and consults worldwide on pain pathways, analgesics, and novel sigma receptor/chaperone compounds, and a novel (BK channel) respiratory stimulant.

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

29.09.2025

Herausgeber

Verlag

Elsevier Science & Technology

Seitenzahl

262

Maße (L/B/H)

23,4/19/1,4 cm

Gewicht

576 g

Sprache

Englisch

ISBN

978-0-443-27412-1

EU-Ansprechpartner

Elsevier B.V.
Radarweg 29
1043 NX Amsterdam
NL
productsafety@elsevier.com

Herstelleradresse

Elsevier Science & Technology
London Wall 125
EC2Y 5AS London
GB
tradeorders@elsevier.com

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  • Produktbild: Kratom
  • Section 1: Background
    1. Botany, geographical distribution, and phytochemistry of Mitragyna speciosa (Korth.) and related species
    Satya Swathi Nadakuduti, Mengzi Zhang, Larissa C. Laforest and Brian Pearson
    2. The scientific evolution of kratom: a historical overview
    Thiruventhan Karunakaran, Yathindra Marimuthu, Balasingam Vicknasingam and Marek C. Chawarski
    3. Recent patterns and reasons for use
    Marc T. Swogger, Kirsten E. Smith, Tianna Torrice and Oliver Grundmann
    Section 2: Basic science
    4. Chemistry and metabolites: ADME
    Manoj Gundeti, Christopher R. Mccurdy and Abhisheak Sharma
    Section 3: Current therapeutic uses
    5. Kratom-related physical dependence and addiction
    Kirsten E. Smith, Darshan Singh and Oliver Grundmann
    6. Current therapeutic uses
    Norsyifa Harun, Siti Rafidah Yusof and Farah Wahida Suhaimi
    Section 4: Pharmaceutical drug development of kratom-derived products
    7. Regulation and policy regarding kratom-derived dietary supplements and direct-to-consumer sales
    Robert Durkin, Oliver Grundmann and Kirsten E. Smith
    8. Patentability and exclusivity of kratom based natural products
    Robert Paradiso
    Section 5: Concerns
    9. Kratom drug-drug (and other) interactions
    Robert B. Raffa and Jeanette Mathews
    10. Susceptible populations
    Robert B. Raffa and Jeanette Mathews
    Section 6: Commentaries/Perspectives
    11. Kratom purity and quality control issues: an in-depth analysis
    Frank Breve
    12. Kratom entrepreneurship | exploiting the commercial potential of kratom and its active alkaloids
    Chad E. Beyer
    13. Equity investment into kratom, mitragynine, and related products
    Zachariah Mcintosh-Pearce
    14. Medical marijuana as a template for understanding kratom
    Soren Shade