Section 1 – Basic Science of Pathologic Myopia. .- Chapter 1. Myopia: A Historical Perspective.- Chapter 2. Definition of pathologic myopia (PM).- Chapter 3. Epidemiology of Myopia, High Myopia and Pathological Myopia.- Chapter 4. Genetics of Pathologic Myopia.- Chapter 5. Public Health Impact of Pathologic Myopia.- Chapter 6. Animal Models of Experimental Myopia: Limitations and Synergies with Studies on Human Myopia.- Chapter 7. The Sclera and its Role in Regulation of the Refractive State.- Section 2 - Ocular Changes in the Development of Pathologic Myopia. .- Chapter 8. Update on the Pathology of Pathological Myopia.- Chapter 9. The Sclera and Induced Abnormalities in Myopia.- Chapter 10. The Choroid Fin.- Chapter 11. Theories of Myopization: Potential Role of a Posterioly Expanding Bruch’s Membrane .- Chapter 12. The Optic Nerve Head in High Myopia / Abnormalities of the Intrapapillary and Parapapillary Region.- Chapter 13. Vitreous Changes in Myopia.- Chapter 14. Ultra-widefield imaging of vitreous in pathologic myopia.- Section 3- Sequella of Pathologic Myopia and Their Potential Treatments. .- Chapter 15.  Staphyloma I.- Chapter 16. Staphyloma II.- Chapter 17. Overview of OCT-based classification of macular lesions due to pathologic myopia.- Chapter 18. Myopic Maculopathy.- Chapter 19. Choroidal Neovascularization.- Chapter 20. Myopic Macular Retinoschisis.- Chapter 21. surgical approaches for complications of PM.- Chapter 22. Peripheral Retinal Abnormalities.- Chapter 23. Retinal Detachment.- Chapter 24. Glaucoma in Myopia.- Chapter 25. Myopic Optic Neuropathy.- Chapter 26. Special Considerations for Cataract Surgery in the Face of Pathologic Myopia.- Chapter 27. Ocular Motility Abnormalities.- Chapter 28. Ocular and Systemic Disease.- Section 4 - Treatment of pathologic myopia. .- Chapter 29. Prevention of myopia progression in children and adolescents.- Chapter 30. OPTICAL METHODS TO SLOW THE PROGRESSION OF MYOPIA.- Chapter 31. Sclera-targeted therapies for pathologic myopia.-