• Preface
• Chapter 1. Virus Shaping History and Discovery of Virus
• 1.1 Virus shaping history
• 1.1.1 Tulipomania: bubbles of bulbs
• 1.1.2 The fall of old Mexico and Peru
• 1.1.3 Succession of thrones
• 1.1.4 The Louisiana Purchase
• 1.2 Discovery of virus
• 1.2.1 The gem theory
• 1.2.2 Discovery of virus
• 1.2.3 Cancer-causing viruses
• 1.2.4 Discovery of retrovirus
• Chapter 2. HIV/AIDS Drugs, Transforming a Death Sentence to a Chronic Disease
• 2.1 Discovery of the virus
• 2.1.1 A death sentence
• 2.1.2 Discovery of HIV and the great scientific controversy
• 2.1.3 The Nobel Prize
• 2.2 The first ray of hope
• 2.2.1 Nucleoside antiviral drugs
• 2.2.2 Non-nucleoside reverse transcriptase inhibitors
• 2.3 HIV protease inhibitors
• 2.3.1 HIV protease
• 2.3.2 First-generation HIV protease inhibitors
• 2.3.3 Second-generation HIV protease inhibitors
• 2.4 HIV integrase inhibitors
• 2.5 HIV Entry Inhibitors
• 2.5.1 HIV fusion inhibitors
• 2.5.2 CCR5 inhibitors
• 2.6 Triumph of modern medicine
• Chapter 3. Hepatitis Drugs
• 3.1 Hepatitis A virus
• 3.1.1 Discovery of hepatitis A virus
• 3.1.2 Hepatitis A vaccines
• 3.2 Hepatitis B virus
• 3.2.1 Discovery of hepatitis B virus
• 3.2.2 Hepatitis B vaccines
• 3.2.3 Hepatitis B drugs
• 3.3 Hepatitis C virus
• 3.3.1 Discovery of Hepatitis C virus
• 3.3.2 Hepatitis C virus NS3/4A protease inhibitors
• 3.3.3 Hepatitis C virus NS5A replication complex inhibitors
• 3.3.4 Hepatitis C virus NS5B polymerase inhibitors
• 3.4 Triumph of modern medicines
• Chapter 4. Influenza: A Perennial Killer
• 4.1 Influenza, a perennial killer
• 4.2 A virus that changed the world: the 1918 Spanish flu pandemic
• 4.3 Discovery of the influenza virus
• 4.4 Influenza vaccines
• 4.4.1 History of vaccination
• 4.4.2 History of influenza vaccines
• 4.4.3 Influenza vaccines today
• 4.5 Influenza drugs
• 4.5.1 M2 inhibitors
• 4.5.2 Influenza virus neuraminidase inhibitors
• Chapter 5. Coronaviruses
• 5.1 Coronavirus Drugs
• 5.1.1. SARS
• 5.1.2. MARS
• 5.1.3. SARS-CoV-2
• 5.2 COVID-19 Vaccines
• 5.2.1. Pfizer/Biotech's mRNA vaccine
• 5.2.2. Johnson and Johnson's viral vector vaccine
• 5.3 COVID-19 Drugs
• 5.3.1. Remdesivir (Veklury)
• 5.3.2. Dexamethasone
• Chapter 6. Closing Remarks
• Bibliography
• Chemical Structures of Antiviral Drugs