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Progranulin Methods and Protocols

Aus der Reihe Methods in Molecular Biology
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139,99 € UVP 160,49 €

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

28.06.2018

Abbildungen

XIII, 363 p. 79 illus., 56 illus. in color.

Herausgeber

Andrew Bateman + weitere

Verlag

Springer Us

Seitenzahl

363

Maße (L/B/H)

26/18,3/2,6 cm

Gewicht

910 g

Sprache

Englisch

ISBN

978-1-4939-8557-9

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

28.06.2018

Abbildungen

XIII, 363 p. 79 illus., 56 illus. in color.

Herausgeber

Verlag

Springer Us

Seitenzahl

363

Maße (L/B/H)

26/18,3/2,6 cm

Gewicht

910 g

Sprache

Englisch

ISBN

978-1-4939-8557-9

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: GPSR Kontakt

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  • Produktbild: Progranulin
  • Produktbild: Progranulin

  • A Brief Overview of Progranulin in Health and Disease.- Chromatographic Methods for the Purification of Granulin Peptides.- Methods for Expression and Purification of Biologically Active Recombinant Progranulin.- Large-Scale Generation of Recombinant Granulin Peptides in
    E. coli
    .- Nuclear Magnetic Resonance Spectroscopy in Analysis of Granulin Three-Dimensional Structure and Cysteine Bridging.- Data Mining: Applying the AD&FTD Mutation Database to Progranulin.- Measurement of Circulating Progranulin (PGRN/GP88/GEP) by Enzyme-Linked Immunosorbent Assay and Application in Human Diseases.- Immunohistochemical Detection of Progranulin (PGRN/GP88/GEP) in Tumor Tissues as a Cancer Prognostic Biomarker.- Analysis of Progranulin-Mediated Akt and MAPK Activation.- Mouse Monoclonal Antibodies Against Progranulin (PGRN/GEP) as Therapeutics in Preclinical Cancer Models.- Methods to Analyze the Role of Progranulin (PGRN/GEP) on Cancer Stem Cell Features.- Methods to Study the Role of Progranulin in the Tumor Microenvironment.- Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo using
    Caenorhabditis elegans.- 
    The Use of Caenorhabditis elegans to Study Progranulin in the Regulation of Programmed Cell Death and Stress Response.- Application of Zebrafish and Knockdown Technology to Define Progranulin Neuronal Function.- Methods to Investigate the Molecular Basis of Progranulin Actions on Brain and Behavior In Vivo Using Knockout Mice.- Methods to Investigate the Protection Againts Neurodegenerative Disorders Provided by Progranulin Gene Transfer in the Brain.- The Interaction between Progranulin with Sortilin and the Lysosome.- Methods to Study the Role of Progranulin in Preimplanatation Mouse Embryo Development.- Establishment of a Modified Collagen-Induced Arthritis Mouse Model to Investigate the Anti-Inflammatory Activity of Progranulinin Inflammatory Arthritis.- Methods for Studying the Function of Progranulin in Atherosclerosis using Both Knockout Mice Models and In Vitro Studies.- Methods to Investigate the Roles of Prgranulin in Angiogenesis Using In Vitro Strategies and Transgenic Mouse Models.