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G-Quadruplex DNA Methods and Protocols

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

23.08.2016

Abbildungen

XII, 276 p.

Herausgeber

Peter Baumann

Verlag

Humana Press

Seitenzahl

276

Maße (L/B/H)

25,4/17,8/1,6 cm

Gewicht

547 g

Auflage

Softcover reprint of the original 1st ed. 2010

Sprache

Englisch

ISBN

978-1-4939-5639-5

Beschreibung

Rezension

From the reviews:

“The book G-Quadruplex DNA … provides an excellent collection of important methods for the study of the DNA G-quadruplex structures. … I definitely recommend this book, which can be considered an outstanding source of information that addresses several problems … in the investigation of G-quadruplex structures. The book is appropriate for everyone working in the area of G-quadruplex research, including biologists, biochemists and chemists since it is a worthy guide for both beginners and experienced scientists interested in studying this increasingly attractive field.” (Aldo Galeone, ChemBioChem, Issue 11, September, 2010)

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

23.08.2016

Abbildungen

XII, 276 p.

Herausgeber

Peter Baumann

Verlag

Humana Press

Seitenzahl

276

Maße (L/B/H)

25,4/17,8/1,6 cm

Gewicht

547 g

Auflage

Softcover reprint of the original 1st ed. 2010

Sprache

Englisch

ISBN

978-1-4939-5639-5

Herstelleradresse

Springer-Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

Email: ProductSafety@springernature.com

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  • Produktbild: G-Quadruplex DNA
  • Produktbild: G-Quadruplex DNA
  • G-Quadruplexes: From Guanine Gels to Chemotherapeutics.- Molecular Modeling and Simulation of G-Quadruplexes and Quadruplex-Ligand Complexes.- Computational Approaches to the Detection and Analysis of Sequences with Intramolecular G-Quadruplex Forming Potential.- Preparation of G-Quartet Structures and Detection by Native Gel Electrophoresis.- Biochemical Techniques for the Characterization of G-Quadruplex Structures: EMSA, DMS Footprinting, and DNA Polymerase Stop Assay.- Real-Time Observation of G-Quadruplex Dynamics Using Single-Molecule FRET Microscopy.- Sedimentation Velocity Ultracentrifugation Analysis for Hydrodynamic Characterization of G-Quadruplex Structures.- 2-Aminopurine as a Probe for Quadruplex Loop Structures.- Assessing DNA Structures with 125I Radioprobing.- Monitoring the Temperature Unfolding of G-Quadruplexes by UV and Circular Dichroism Spectroscopies and Calorimetry Techniques.- Probing Telomeric G-Quadruplex DNA Structures in Cells with In Vitro Generated Single-Chain Antibody Fragments.- Detection of G-Quadruplexes in Cells and Investigation of G-Quadruplex Structure of d(T2AG3)4 in K+ Solution by a Carbazole Derivative: BMVC.- Isolation of G-Quadruplex DNA Using NMM-Sepharose Affinity Chromatography.- Quantifying Interactions Between G-Quadruplex DNA and Transition-Metal Complexes.- G4-FID: A Fluorescent DNA Probe Displacement Assay for Rapid Evaluation of Quadruplex Ligands.