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Next Generation Sequencing in Cancer Research Volume 1: Decoding the Cancer Genome

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

25.08.2015

Abbildungen

XII, 383 p.

Herausgeber

Wei Wu + weitere

Verlag

Springer Us

Seitenzahl

383

Maße (L/B/H)

23,5/15,5/2,2 cm

Gewicht

598 g

Sprache

Englisch

ISBN

978-1-4899-8808-9

Beschreibung

Portrait

Wei Wu, M.D., Ph.D. is a Research Associate for the Department of Bio Science at the University of Calgary, specializing in the cancer genome and systems biology. He has edited two volumes with Springer. In addition, he's a member of various editorial board for journals including the International Journal of Biomedical Sciences, International Journal of Molecular Medicine and Advances in Sciences and the Research Journal of Biological Sciences. Hani Choudhry, D.Phil is a member of the Genomics Research Group at the Wellcome Trust Centre for Human Genetics at Oxford University. His expertise is in high throughput next generation sequencing.

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

25.08.2015

Abbildungen

XII, 383 p.

Herausgeber

Verlag

Springer Us

Seitenzahl

383

Maße (L/B/H)

23,5/15,5/2,2 cm

Gewicht

598 g

Sprache

Englisch

ISBN

978-1-4899-8808-9

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: GPSR Kontakt

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  • Produktbild: Next Generation Sequencing in Cancer Research
  • Produktbild: Next Generation Sequencing in Cancer Research
  • Introduction: next generation sequencing technology and cancer research.- The majority of total nuclear-encoded non-ribosomal RNA in a human cell is ‘dark matter’ unannotated RNA.- Total RNA-seq of breast cancer in hypoxia.- Altered antisense-to-sense transcript ratios in breast cancer.- Identification of piRNAs in Hela cells by massive parallel sequencing.- Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia.- Whole-Exome Sequencing Identifies FAM20A Mutations as a Cause of Amelogenesis Imperfecta and Gingival Hyperplasia Syndrome.- Whole-exome sequencing in CIC and IDH1/2 contributing to human oligodendroglioma.- Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencing.- Tumour evolution inferred by single-cell sequencing.- Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq.- Tracing the derivation of embryonic stem cells from the inner cell mass by single-cell RNASeq analysis.- Whole genome DNA methylation analysis based on high throughput sequencing technology.- Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors.- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.- MicroRNA transfection and AGO-bound CLIP-seq data sets reveal distinct determinants of miRNA action.- Genome-wide identification of polycomb-associated RNAs by RIP-seq.- Single-molecule sequencing: sequence methods to enable accurate quantisation.- Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells.- Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.- The genome information process for cancer research: the challenge and perspective.- Index.