Acetaldehyde-Related Pathology Bridging the Trans-Disciplinary Divide
Aus der Reihe
Novartis Foundation Symposium
163,99 €
inkl. gesetzl. MwSt.Beschreibung
Produktdetails
Format
Kopierschutz
Ja
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
30.04.2007
Herausgeber
Derek J. Chadwick + weitereVerlag
John Wiley & Sons IncSeitenzahl
286 (Printausgabe)
Dateigröße
1741 KB
Auflage
8. Auflage
Sprache
Englisch
EAN
9780470511831
Part of the prestigious Novartis Foundation, this is the first book
to review the pathology associated with acetaldehyde, a known toxic
agent found in cigarette smoke and other pollutants and derived
from ingested alcohol, amongst other sources. In the body,
acetaldehyde affects several tissues, particularly the brain and
liver, causing various diseases, including cancer, alcoholic liver
disease and Alzheimer's.
Acetaldehyde-Related Pathology describes the toxic
effects of acetaldehyde at the tissue and cellular levels,
reviewing enzyme biochemistry, transgenic mouse models of alcohol
dehydrogenase mutants, and the cell-signalling pathways implicated
in alcohol-related pathology. It explores the mechanisms of
acetaldehyde-induced damage to tissues, often a first step in
carcinogenesis, including the oral cavity, the human airway, and
the GI tract. The book considers pharmacological strategies and
treatments for reducing oral and intestinal acetaldehyde.
Acetaldehyde-Related Pathology features in-depth,
round-table discussions by an international array of scientists
from major laboratories worldwide involved in studies of
acetaldehyde-related pathology.
This book is essential reading for anyone interested in the
effects of this compound - pathologists, biochemists,
toxicologists, cell and molecular biologists.
to review the pathology associated with acetaldehyde, a known toxic
agent found in cigarette smoke and other pollutants and derived
from ingested alcohol, amongst other sources. In the body,
acetaldehyde affects several tissues, particularly the brain and
liver, causing various diseases, including cancer, alcoholic liver
disease and Alzheimer's.
Acetaldehyde-Related Pathology describes the toxic
effects of acetaldehyde at the tissue and cellular levels,
reviewing enzyme biochemistry, transgenic mouse models of alcohol
dehydrogenase mutants, and the cell-signalling pathways implicated
in alcohol-related pathology. It explores the mechanisms of
acetaldehyde-induced damage to tissues, often a first step in
carcinogenesis, including the oral cavity, the human airway, and
the GI tract. The book considers pharmacological strategies and
treatments for reducing oral and intestinal acetaldehyde.
Acetaldehyde-Related Pathology features in-depth,
round-table discussions by an international array of scientists
from major laboratories worldwide involved in studies of
acetaldehyde-related pathology.
This book is essential reading for anyone interested in the
effects of this compound - pathologists, biochemists,
toxicologists, cell and molecular biologists.
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