Molecular Clocks and Light Signalling
Aus der Reihe
Novartis Foundation Symposium
161,99 €
inkl. gesetzl. MwSt.Beschreibung
Produktdetails
Format
Kopierschutz
Ja
Family Sharing
Nein
Text-to-Speech
Nein
Erscheinungsdatum
25.06.2004
Herausgeber
Derek J. Chadwick + weitereVerlag
Wiley-IsteSeitenzahl
306 (Printausgabe)
Dateigröße
3929 KB
Auflage
1. Auflage
Sprache
Englisch
EAN
9780470090824
The ability at the molecular level to keep track of time is a
property shared by organisms ranging from the simplest unicells to
humans. The primary feature of these biological clocks is their
ability to entrain to environmental stimuli. The dominant stimulus
comes from environmental light cues, which requires the existence
of photopigments sensitive to light. The exact identity of the
molecules involved in circadian photoreception has remained
elusive.
The classical view of the circadian system is of diverse
physiological rhythms regulated by a centralized clock structure.
This book presents evidence that challenges this view. Experiments
in both vertebrate and invertebrate systems demonstrate that the
circadian timing system is dispersed throughout the animal and
suggest that possibly every cell contains an autonomous clock
mechanism. A variety of tissues and cells contain have been shown
to maintain an oscillation when placed in vitro and removed from
any external cues or signals that originate from the classical
clock structures and/or the environment.
This book draws together contributions from an international and
interdisciplinary group of experts whose work is focused on all
aspects of the topic. Coverage includes the mechanisms of light
signalling to the vertebrate clock, the connections between central
and peripheral clocks, circadian gene expression patterns and
output pathways of clock mechanisms.
property shared by organisms ranging from the simplest unicells to
humans. The primary feature of these biological clocks is their
ability to entrain to environmental stimuli. The dominant stimulus
comes from environmental light cues, which requires the existence
of photopigments sensitive to light. The exact identity of the
molecules involved in circadian photoreception has remained
elusive.
The classical view of the circadian system is of diverse
physiological rhythms regulated by a centralized clock structure.
This book presents evidence that challenges this view. Experiments
in both vertebrate and invertebrate systems demonstrate that the
circadian timing system is dispersed throughout the animal and
suggest that possibly every cell contains an autonomous clock
mechanism. A variety of tissues and cells contain have been shown
to maintain an oscillation when placed in vitro and removed from
any external cues or signals that originate from the classical
clock structures and/or the environment.
This book draws together contributions from an international and
interdisciplinary group of experts whose work is focused on all
aspects of the topic. Coverage includes the mechanisms of light
signalling to the vertebrate clock, the connections between central
and peripheral clocks, circadian gene expression patterns and
output pathways of clock mechanisms.
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