• Produktbild: Stroke Genomics
  • Produktbild: Stroke Genomics
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Stroke Genomics Methods and Reviews

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

10.11.2010

Abbildungen

X, 65 illus., schwarz-weiss Illustrationen

Herausgeber

Simon J. Read + weitere

Verlag

Humana Press

Seitenzahl

351

Maße (L/B/H)

23,5/15,5/2,3 cm

Gewicht

618 g

Auflage

Softcover reprint of hardcover 1st edition 2005

Sprache

Englisch

ISBN

978-1-61737-500-2

Beschreibung

Rezension

From the reviews:


"The protocols presented in Stroke Genomics: Methods and Reviews will greatly benefit scientists interested in the molecular biology as well as the genetic and genomic basis of strokes." - Journal of Chemical Neuroanatomy

"...very interesting and informative...an attractive and interesting overview of the different aspects of the current stroke research...can be recommended as a source of useful and up-to-date practical and theoretical information on stroke genetics and on stroke associated gene expression." - European Neurology


"This book gives the opportunity for experts in the field to explore the practical and experimental applications of genomic and molecular biology research to the treatment of stroke. … The book also indicates detailed methods for studying the molecular biology of stroke. … It can be recommended if one is interested in the basic scientific background that underlies central nervous system pathology … ." (J. V. Byrne, Neuroradiology, Vol. 47, 2005)

Portrait

Leading experts explore the pragmatic application of the tools of genomic and molecular biology research to the treatment of stroke. The authors relate changes in gene expression to physiological endpoints-such as functional imaging paradigms-to produce a more holistic approach in which molecular biology goes hand-in-hand with stroke pathophysiology. The book shows how to successfully design, execute, and interpret preclinical and clinical molecular biological studies of stroke as well as rapid development of the next generation of stroke therapeutics.

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

10.11.2010

Abbildungen

X, 65 illus., schwarz-weiss Illustrationen

Herausgeber

Verlag

Humana Press

Seitenzahl

351

Maße (L/B/H)

23,5/15,5/2,3 cm

Gewicht

618 g

Auflage

Softcover reprint of hardcover 1st edition 2005

Sprache

Englisch

ISBN

978-1-61737-500-2

Herstelleradresse

Springer-Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

Email: [email protected]

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  • Produktbild: Stroke Genomics
  • Produktbild: Stroke Genomics
  • Part I. Introduction

    Introduction to Stroke Genomics
    Simon J. Read and Frank C. Barone

    Part II. Preclinical Models and Gene Manipulation

    Choice, Methodology, and Characterization of Focal Ischemic Stroke Models: The Search for Clinical Relevance
    David Virley

    Mutant Animal Models of Stroke and Gene Expression: The Stroke-Prone Spontaneously Hypertensive Rat
    Hilary V. O. Carswell, Martin W. McBride, Delyth Graham, Anna F. Dominiczak, and I. Mhairi Macrae

    Gene Therapy in Neurological Disease
    Midori A. Yenari and Robert M. Sapolsky

    Stem Cell Transplantation After Middle Cerebral Artery Occlusion
    Paul Stroemer and Helen Hodges

    Endogenous Brain Protection: Models, Gene Expression, and Mechanisms
    Frank C. Barone

    Production of Transgenic and Mutant Mouse Models
    Alex J. Harper

    3-Nitropropionic Acid Model of Metabolic Stress: Assessment by Magnetic Resonance Imaging
    Toby John Roberts

    Part III. Clinical Paradigms

    Practicalities of Genetic Studies in Human Stroke
    Ahamad Hassan and Hugh S. Markus

    Evaluation of the Interactions of Common Genetic Mutations in Stroke
    Zoltán Szolnoki

    Part IV. Assessing Differential Expression

    Technologies of Disease-Related Gene Discovery Using Preclinical Models of Stroke
    Xinkang Wang

    Quantitative Analysis of Gene Transcription in Stroke Models Using Real-Time RT-PCR
    David C. Harrison and Brian C. Bond

    Effective Analysis of Genomic Data
    Paul R. Nelson, Andrew B. Goulter, and Richard J. Davis

    Bioinformatic Approaches to Assigning Protein Function From Novel Sequence Data
    David Michalovich and Richard Fagan

    Pragmatic Target Discovery From Novel Gene to Functionally Defined Drug Target: The Interleukin-1 Story
    Stuart McRae Allan

    Indexƒ