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Oligonucleotide Synthesis Methods and Applications

Aus der Reihe Methods in Molecular Biology
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157,99 € UVP 181,89 €

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

10.11.2010

Abbildungen

XVI, 436 p. 142 illus.

Herausgeber

Piet Herdewijn

Verlag

Humana Press

Seitenzahl

436

Maße (L/B/H)

22,9/15,2/2,3 cm

Gewicht

599 g

Auflage

Softcover reprint of hardcover 1st ed. 2005

Sprache

Englisch

ISBN

978-1-61737-441-8

Beschreibung

Portrait

Piet Herdewijn is Professor at the Katholieke Universiteit Leuven, Belgium, and head of the laboratory of medicinal chemistry at the Rega Institute. He obtained his Ph.D. and habilitation from the same university. He was a postdoctoral fellow of the Humboldt Foundation at the University of Konstanz. He has conducted research in bioorganic and medicinal chemistry, mainly in the field of nucleosides, nucleotides, and nucleic acids, at the University of Leuven, the University of Ghent, and the Université d'Evry-Val-d'Essonne.

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

10.11.2010

Abbildungen

XVI, 436 p. 142 illus.

Herausgeber

Piet Herdewijn

Verlag

Humana Press

Seitenzahl

436

Maße (L/B/H)

22,9/15,2/2,3 cm

Gewicht

599 g

Auflage

Softcover reprint of hardcover 1st ed. 2005

Sprache

Englisch

ISBN

978-1-61737-441-8

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Oligonucleotide Synthesis
  • Produktbild: Oligonucleotide Synthesis
  • Synthesis of DNA Using a New Two-Step Cycle.- RNA Synthesis Using 2?-O-(Tert-Butyldimethylsilyl) Protection.- RNA Oligonucleotide Synthesis Via 5?-Silyl-2?-Orthoester Chemistry.- Dimethylthiarum Disulfide.- Assay for Evaluating Ribonuclease H-Mediated Degradation of RNA-Antisense Oligonucleotide Duplexes.- Di- and Oligonucleotide Synthesis Using H-Phosphonate Chemistry.- Solid-Phase Synthesis of Circular Oligonucleotides.- Locked Nucleic Acid Synthesis.- Synthesis of DNA Mimics Representing HypNA-pPNA Hetero-Oligomers.- Base-Modified Oligonucleotides With Increased Duplex Stability.- of Hypermodified Nucleotides in RNA.- Chemical Methods for Peptide-Oligonucleotide Conjugate Synthesis.- Biotin-Labeled Oligonucleotides With Extraordinarily Long Tethering Arms.- Universal Labeling Chemistry for Nucleic Acid Detection on DNA Chips.- Postsynthetic Functionalization of Triple Helix-Forming Oligonucleotides.- Fluorescence-Based On-Line Detection as an Analytical Tool in RNA Electrophoresis.- Design and Optimization of Molecular Beacon Real-Time Polymerase Chain Reaction Assays.- High-Throughput Production of Optimized Primers (Fimers) for Whole-Genome Direct Sequencing.- Nonenzymatic Template-Directed RNA Synthesis.- DNase I Footprinting of Small Molecule Binding Sites on DNA.- Gene Targeting Using Peptide Nucleic Acid.- Nucleic Acid Library Construction Using Synthetic DNA Constructs.- In Vitro Selection From Combinatorial Nucleic Acid Libraries.- In Vitro Selection Procedures for Identifying DNA and RNA Aptamers Targeted to Nucleic Acids and Proteins.- Short Double-Stranded Ribonucleic Acid as Inhibitor of Gene Expression by the Interference Mechanism.