Coronavirus Replication and Reverse Genetics
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- Hardcover
- Taschenbuch ausgewählt
- eBook
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Sprache:Englisch
147,99 €
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
19.10.2010
Abbildungen
XI, 257 p. 49 illus., 18 illus. in color.
Herausgeber
Luis EnjuanesVerlag
Springer BerlinSeitenzahl
257
Maße (L/B/H)
23,5/15,5/1,7 cm
Gewicht
467 g
Auflage
Softcover reprint of hardcover 1st edition 2005
Sprache
Englisch
ISBN
978-3-642-05997-1
Coronaviruses are the RNA viruses with the largest genome known to date (27 to 32 kb). Members of this virus family affect most domestic animal species, causing important socio-economical losses, and also infect humans. Human coronaviruses were known to cause the winter common cold, a mild infection without important pathological consequences except in immuno-compromised patients. Recently, two new human coronaviruses have emerged, one causing the Severe and Acute Respiratory Syndrome (SARS) that infected more than 8000 individuals, leading to more than 800 deaths in 32 countries. This epidemic mobilized the World Health Organization, which launched travel restrictions to certain parts of the world for the first time in the last 50 years. The fact that coronaviruses, as many other viruses, crossed the species barrier to infect humans has posed a serious challenge to scientists involved in animal and human health. Control of coronavirus-induced diseases can only be the consequence of research on virus molecular biology and pathogenesis. This book contains information on virus genome structure, mechanism of replication and transcription, and the development of tools that make possible reverse genetic studies to understand virus-host interactions and the molecular basis of virus pathogenesis. The book also provides essential information for the development of classical and recombinant vaccines to control coronavirus infections.
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