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Produktbild: Molecular Targeting in Oncology
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Molecular Targeting in Oncology

Aus der Reihe Cancer Drug Discovery and Development
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185,99 € UVP 213,99 €

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

07.01.2008

Abbildungen

XVI, 68 schwarzweisse Abbildungen, 66 Tabellen, 4 Abbildungenton-Abb., 64 schwarzweisse Zeichnungen 254 mm

Herausgeber

Howard L. Kaufman + weitere

Verlag

Humana Press

Seitenzahl

728

Maße (L/B/H)

26,2/18,7/3,4 cm

Gewicht

1671 g

Auflage

2008

Sprache

Englisch

ISBN

978-1-58829-577-4

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

07.01.2008

Abbildungen

XVI, 68 schwarzweisse Abbildungen, 66 Tabellen, 4 Abbildungenton-Abb., 64 schwarzweisse Zeichnungen 254 mm

Herausgeber

Verlag

Humana Press

Seitenzahl

728

Maße (L/B/H)

26,2/18,7/3,4 cm

Gewicht

1671 g

Auflage

2008

Sprache

Englisch

ISBN

978-1-58829-577-4

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Molecular Targeting in Oncology
  • Table of Contents

    Section 1 General Strategies for Molecular Targeting in Oncology

    Chapter 1 The Cell Cycle: Therapeutic Targeting of Cell Cycle
    Regulatory Components and Effector Pathways in Cancer
    Chad D. Knights and Richard G. Pestell
    Chapter 2 mTOR: Properties and Therapeutics
    John B. Easton and Peter J. Houghton

    Chapter 3 Ras/Raf/MEK Inhibitors
    Joseph A. Sparano

    Chapter 4 17AAG: Targeting the Molecular Chaperone Heat Shock Protein 90
    Len Neckers and Percy Ivy
    Chapter 5 The Cancer Epigenome: Can it be targeted for therapy?
    Sam Thiagalingam and Douglas V. Faller

    Section 2 Molecular Targeting for Specific Disease Sites

    Chapter 6 Molecular targeting in upper gastrointestinal malignancies
    Scott Wadler

    Chapter 7 Molecular Targeting of Colorectal Cancer: An Idea Whose Time
    Has Come
    Mark L. Sundermeyer, Alfonso Bellacosa, and Neal J. Meropol

    Chapter 8 Molecular Targeting in Hepatocellular Carcinoma
    Jonathan D. Schwartz. and Josep M. Llovet

    Chapter 9 Molecularly Targeted Therapy in Pancreatic Cancer
    Anupama Goel and Peter Kozuch

    Chapter 10 Untargeted Use of Targeted Therapy: A Dilemma in Non-Small
    Cell Lung Cancer
    Cheryl Ho, Angela M. Davies, Primo N. Lara, O. Gautschi, P.C. Mack,
    Paul H. Gumerlock and David R. Gandara

    Chapter 11 Molecular Targeting in Oncology: Renal Cell Cancer
    Olwen Hahn and Walter Stadler

    Chapter 12 Targeted Therapies for Prostate Cancer
    Elisabeth I. Heath and Michael A. Carducci

    Chapter 13 Molecular Targets in Ovarian Cancer and Endometrial Cancer
    Nilofer S. Azad, Gisele Sarosy, and Elise C. Kohn

    Chapter 14 Targeted Therapy for Breast Cancer
    Deena M. Atieh and Linda T. Vahdat

    Chapter 15 Melanoma
    Akshay Gupta and John M. Kirkwood

    Section 3 Classes of Drugs for Molecular Targeting in Oncology

    Chapter 16 Antibody Therapy of Cancer
    Hossein Borghaei, Liat Binyamin, Igor Astsaturov, and Louis M. Weiner

    Chapter 17 Nucleic Acid Therapies for Cancer Treatment
    Dan T. Vogl and Alan M. Gewirtz

    Chapter 18 Engineering Oncolytic Measles Viruses for Targeted Cancer
    Therapy
    Takafumi Nakamura and Stephen J. Russell

    Chapter 19 Vaccines as Targeted Cancer Therapy
    Miguel-Angel Perales, Jedd D. Wolchok and Howard L. Kaufman

    Chapter 20 Cytokine based therapy for cancer
    Henry B. Koon and Michael B. Atkins

    Chapter 21 Cyclooxygenase-2 (Cox-2) as a Target for Cancer Prevention
    and Treatment
    Monica Bertagnolli, Jaye L. Viner, and Ernest T. Hawk

    Section 4 Specific Drugs for Molecular Targeting in Oncology

    Chapter 22 Imatinib Mesylate (Gleevec) and the emergence of
    chemotherapeutic drug-resistant mutation
    Gerald V. Denis

    Chapter 23 Development of a Targeted Treatment for Cancer: The Example
    of C225 (Cetuximab)
    John Mendelsohn

    Chapter 24 VEGF Inhibition for Cancer Therapy
    Shermini Saini and Herbert Hurwitz

    Chapter 25 Somatostatin analogue therapy
    Manish C. Champaneria, M.D., Irvin M. Modlin, M.D., Ph.D., D.Sc., Igor
    Latich, M.D., Jan Bornschein, Ignat Drozdov, Mark Kidd, Ph.D.

    Section 5 Challenges in Molecular Targeting in Oncology

    Chapter 26 Patient Selection for Rational Development of Novel
    Anticancer Agents
    Grace K. Dy and Alex A. Adjei

    Chapter 27 Clinical Trial Design with Targeted Agents
    Sarita Dubey and Joan H. Schiller

    Chapter 28 How to define treatment success or failure if tumors don't
    shrink: Consequences for trial design.
    JJEM Kitzen, MJA de Jonge, and J Verweij

    Chapter 29 Molecular Imaging in Oncology
    Lalitha Shankar, Anne Menkens, and Daniel C. Sullivan

    Chapter 30 Combinations of Molecular Targeted Therapies - Opportunities
    and Challenges
    Helen X. Chen and Janet E. Dancey

    Chapter 31 Preclinical Development of Molecularly Targeted Agents