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Produktbild: Molecular Profiling
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Molecular Profiling Methods and Protocols

Aus der Reihe Methods in Molecular Biology
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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

12.11.2011

Herausgeber

Virginia Espina + weitere

Verlag

Humana Press

Seitenzahl

447

Maße (L/B/H)

26/18,3/3 cm

Gewicht

1063 g

Auflage

2012

Sprache

Englisch

ISBN

978-1-60327-215-5

Beschreibung

Rezension

From the reviews:

“This informative book combines genomics, proteomics, and bioinformatics with experimental protocols and detailed discussions regarding future challenges in commercialization and practical use in the field with an emphasis on tissue-based molecular profiling. … readers can use this as a practical guide at the laboratory bench as well as in the boardroom. The book is written for scientists, pathologists, oncologists, biotechnologists, residents, medical students, and nurses involved in clinical trial research. … This will be a valuable tool for those involved in clinical trial research.” (Omer Iqbal, Doody’s Book Reviews, April, 2012)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

12.11.2011

Herausgeber

Verlag

Humana Press

Seitenzahl

447

Maße (L/B/H)

26/18,3/3 cm

Gewicht

1063 g

Auflage

2012

Sprache

Englisch

ISBN

978-1-60327-215-5

Herstelleradresse

Springer-Verlag GmbH
Tiergartenstr. 17
69121 Heidelberg
DE

Email: ProductSafety@springernature.com

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  • Produktbild: Molecular Profiling
  • Contents
    Preface
    Contributors
    1.      Tumor Staging and Grading: A Primer
                Stacy M. Cowherd
    2.      Clinical Trial Design in the Age of Molecular Profiling
                Alexander Spira and Kirsten H. Edmiston
    3.      Personalized Medicine: Ethics for Clinical Trials
                G. Terry Sharrer
    4.      Reduction of Preanalytical Variability in Specimen Procurement for Molecular Profiling
                Virginia Espina and Claudius Mueller
    5.      The Human Side of Cancer Biobanking
                Eoin Gaffney, Deirdre Madden, and Geraldine A. Thomas
    6.      Introduction to Genomics
                Luca Del Giacco and Cristina Cattaneo
    7.      Genomic Profiling: cDNA arrays and oligoarrays
                Francesco Gorreta, Walter Carbone, Dagania Barzhagi
    8.      Genome wide methylation profiling in archival formalin fixed paraffin embedded (FFPE) tissue samples
    J. Keith Killian, Robert L. Walker, Sven Bilke, Yidong Chen, Sean Davis, Robert Cornelison, William I. Smith, and Paul S. Meltzer
    9.      An Overview of microRNA Methods: Expression Profiling and Target Identification
          Sinéad M Smith and David W Murray
    10.  Antibody Validation by Western Blotting
                Michele Signore and K. Alex Reeder
    11.  Laser Capture Microdissection: ArcturusXT infra-red capture and UV cutting methods
                Rosa I. Gallagher, Steven R. Blakely, Lance A. Liotta, and Virginia Espina
    12.  Antibody microarrays: Analysis of Cystic Fibrosis
    Catherine E. Jozwik, Harvey B. Pollard, Meera Srivastava, Ofer Eidelman, QingYuan Fan, Thomas N. Darling, and Pamela L. Zeitlin
    13.  Tissue Microarrays As A Tool In The Discovery & Validation Of Predictive Biomarkers
                Stephen M. Hewitt
    14.  Reverse phase protein microarrays
                Mariaelena Pierobon, Francesca Galdi, Noemi Moroni, and Emanuel F. Petricoin III
    15.  Serum Low Molecular Weight Protein Fractionation for Biomarker Discovery
    Amy VanMeter, Serena Camerini, Maria Letizia Polci, Alessandra Tessitore, Nishant Trivedi, Michael Heiby, Jonathan Hansen, and Weidong Zhou
    16.  Mass spectrometry based biomarker discovery
                Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo
    17.  Mitochondrial Proteome:  Toward The Detection and Profiling of Disease Associated Alterations
                Paul C. Herrmann and E. Clifford Herrmann
    18.  Adult Neural Stem Cells: Isolation and Propagation
                Jamin M. Lechter and Daniel N. Cox
    19.  Evanescent Wave Imaging: An Introduction to Total Internal Reflection Fluorescence Microscopy (TIRF)
                Bryan A. Millis
    20.  Construction and Hyperspectral Imaging of Quantum Dot Lysate Arrays
                Kevin P. Rosenblatt, Michael Huebschman, and Harold R. Garner
    21.  Microarray Data Analysis: Comparing Two Population Means
                Jianghong Deng, Valerie S. Calvert and Mariaelena Pierobon
    22.  Bioinformatics/Biostatistics: microarray analysis
                Gabriel S. Eichler
    23.  Structure-based functional design of drugs: from target to lead compound
                Amy C. Anderson
    24.  Personalized Medicine: Changing the Paradigm of Drug Development
                Robin Couch and Bryan T. Mott
    25.  Grant Writing Tips for the First Time Applicant
                Lindsay Wescott and Michael Laskofski
    26.  Inventions and Patents: A practical tutorial
                J. Lille Tidwell and Lance Liotta
    27.  Regulatory Approval Pathways for Molecular Diagnostic Technology
                Lance Liotta and Emanuel Petricoin
    28.  Small business development for molecular diagnostics
                Athanasia Anagnostou and Lance Liotta