Platelets
Herausgeber: Michelson, Alan D; Newman, Peter; Frelinger, Andrew; Cattaneo, Marco
Platelets
Herausgeber: Michelson, Alan D; Newman, Peter; Frelinger, Andrew; Cattaneo, Marco
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Comprehensive and definitive source of state-of-the-art knowledge about platelets Integrates the entire field of platelet biology, pathophysiology, and clinical medicine Written for clinicians, pathologists and scientists by 142 world-renowned experts from 18 countries Completely revised and updated, with 11 new chapters on topics such as platelet glycobiology, the platelet transcriptome, platelet inhibitory receptors, platelet function testing in clinical research trials, therapeutic platelet-rich plasma in wound healing, and new antiplatelet drugs Full color textbook with over 250 illustrations and 15,000 references…mehr
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- Produktdetails
- Verlag: Elsevier Science Publishing Co Inc
- 4 ed
- Seitenzahl: 1268
- Erscheinungstermin: 28. März 2019
- Englisch
- Abmessung: 284mm x 222mm x 56mm
- Gewicht: 2664g
- ISBN-13: 9780128134566
- ISBN-10: 0128134569
- Artikelnr.: 54588170
- Verlag: Elsevier Science Publishing Co Inc
- 4 ed
- Seitenzahl: 1268
- Erscheinungstermin: 28. März 2019
- Englisch
- Abmessung: 284mm x 222mm x 56mm
- Gewicht: 2664g
- ISBN-13: 9780128134566
- ISBN-10: 0128134569
- Artikelnr.: 54588170
Megakaryocyte Development and Platelet Formation 3. The Structure of
Resting and Activated Platelets 4. Platelet Glycobiology and the Control of
Platelet Function and Lifespan 5. Platelet Genomics 6. Platelet MicroRNAs
7. The Platelet Transcriptome in Health and Disease 8. The Platelet
Proteome 9. Platelet Receptors 10. The Glycoprotein Ib-IX-V Complex 11.
GPVI and CLEC-2 12. Integrin aIIbß3 13. Protease-Activated Receptors 14.
The Platelet P2 Receptors 15. Platelet Inhibitory Receptors 16.
Interactions Between Platelets, Leukocytes, and the Endothelium 17.
Inhibition of Platelet Function by the Endothelium 18. Platelet Signal
Transduction 19. Platelet Secretion 20. Hemostatic Thrombus Formation in
Flowing Blood 21. Interactions Between Platelets and the Coagulation System
22. Platelet-Derived Extracellular Vesicles 23. Regulation of Fibrinolysis
by Platelets 24. The Role of Platelets in Angiogenesis 25. Platelet
Function in the Newborn
PART II: The Role of Platelets in Disease 26. The Role of Platelets in
Atherothrombosis 27. The Role of Platelets in Diabetes Mellitus 28. The
Role of Platelets in Inflammation 29. The Role of Platelets in
Antimicrobial Host Defense 30. The Role of Platelets in Tumor Growth,
Metastasis, and Immune Evasion 31. The Role of Platelets in Sickle Cell
Disease
PART III: Clinical Tests of Platelet Function 32. Platelet Counting 33.
Clinical Tests of Platelet Function 34. Platelet Aggregation 35. Flow
Cytometry 36. Laboratory Monitoring of Antiplatelet Therapy 37. Platelet
Function Testing in Clinical Research Trials
PART IV: Disorders of Platelet Number and/or Function 38. The Clinical
Approach to Disorders of Platelet Number and Function 39. Immune
Thrombocytopenia (ITP) 40. Drug-Induced Thrombocytopenia 41.
Heparin-Induced Thrombocytopenia 42. Thrombotic Thrombocytopenic Purpura
and Hemolytic-Uremic Syndromes 43. Thrombocytopenia in Pregnancy 44.
Thrombocytopenia in the Newborn 45. Alloimmune Thrombocytopenia 46.
Inherited Thrombocytopenias 47. Thrombocytosis and Essential
Thrombocythemia 48. Inherited Disorders of Platelet Function 49. Acquired
Disorders of Platelet Function
PART V: Antiplatelet Therapy 50. Aspirin 51. P2Y12 Antagonists 52. aIIbß3
(GPIIb-IIIa) Antagonists 53. PAR-1 Antagonists 54. Phosphodiesterase
Inhibitors 55. Novel Antiplatelet Therapies 56. Antiplatelet Drugs in the
Management of Coronary Artery Disease 57. Antiplatelet Drugs in the
Management of Cerebral Ischemia 58. Antiplatelet Drugs in the Management of
Thrombotic/Ischemic Events in Peripheral Artery Disease 59. Antiplatelet
Drugs in the Management of Venous Thromboembolism, Cardioembolism,
Ventricular Assist Devices, and Pregnancy Complications 60. Antiplatelet
Drugs in the Management of Thrombotic/Ischemic Events in Children
PART VI: Therapy to Increase Platelet Numbers and/or Function 61.
Thrombopoietin Receptor Agonists 62. Desmopressin (DDAVP) 63. Factor VIIa
64. Platelet Transfusion Medicine 65. Therapeutic Platelet-Rich Plasma in
Wound Healing 66. Stem Cell-Derived Platelets 67. Gene Therapy for Platelet
Disorders
Megakaryocyte Development and Platelet Formation 3. The Structure of
Resting and Activated Platelets 4. Platelet Glycobiology and the Control of
Platelet Function and Lifespan 5. Platelet Genomics 6. Platelet MicroRNAs
7. The Platelet Transcriptome in Health and Disease 8. The Platelet
Proteome 9. Platelet Receptors 10. The Glycoprotein Ib-IX-V Complex 11.
GPVI and CLEC-2 12. Integrin aIIbß3 13. Protease-Activated Receptors 14.
The Platelet P2 Receptors 15. Platelet Inhibitory Receptors 16.
Interactions Between Platelets, Leukocytes, and the Endothelium 17.
Inhibition of Platelet Function by the Endothelium 18. Platelet Signal
Transduction 19. Platelet Secretion 20. Hemostatic Thrombus Formation in
Flowing Blood 21. Interactions Between Platelets and the Coagulation System
22. Platelet-Derived Extracellular Vesicles 23. Regulation of Fibrinolysis
by Platelets 24. The Role of Platelets in Angiogenesis 25. Platelet
Function in the Newborn
PART II: The Role of Platelets in Disease 26. The Role of Platelets in
Atherothrombosis 27. The Role of Platelets in Diabetes Mellitus 28. The
Role of Platelets in Inflammation 29. The Role of Platelets in
Antimicrobial Host Defense 30. The Role of Platelets in Tumor Growth,
Metastasis, and Immune Evasion 31. The Role of Platelets in Sickle Cell
Disease
PART III: Clinical Tests of Platelet Function 32. Platelet Counting 33.
Clinical Tests of Platelet Function 34. Platelet Aggregation 35. Flow
Cytometry 36. Laboratory Monitoring of Antiplatelet Therapy 37. Platelet
Function Testing in Clinical Research Trials
PART IV: Disorders of Platelet Number and/or Function 38. The Clinical
Approach to Disorders of Platelet Number and Function 39. Immune
Thrombocytopenia (ITP) 40. Drug-Induced Thrombocytopenia 41.
Heparin-Induced Thrombocytopenia 42. Thrombotic Thrombocytopenic Purpura
and Hemolytic-Uremic Syndromes 43. Thrombocytopenia in Pregnancy 44.
Thrombocytopenia in the Newborn 45. Alloimmune Thrombocytopenia 46.
Inherited Thrombocytopenias 47. Thrombocytosis and Essential
Thrombocythemia 48. Inherited Disorders of Platelet Function 49. Acquired
Disorders of Platelet Function
PART V: Antiplatelet Therapy 50. Aspirin 51. P2Y12 Antagonists 52. aIIbß3
(GPIIb-IIIa) Antagonists 53. PAR-1 Antagonists 54. Phosphodiesterase
Inhibitors 55. Novel Antiplatelet Therapies 56. Antiplatelet Drugs in the
Management of Coronary Artery Disease 57. Antiplatelet Drugs in the
Management of Cerebral Ischemia 58. Antiplatelet Drugs in the Management of
Thrombotic/Ischemic Events in Peripheral Artery Disease 59. Antiplatelet
Drugs in the Management of Venous Thromboembolism, Cardioembolism,
Ventricular Assist Devices, and Pregnancy Complications 60. Antiplatelet
Drugs in the Management of Thrombotic/Ischemic Events in Children
PART VI: Therapy to Increase Platelet Numbers and/or Function 61.
Thrombopoietin Receptor Agonists 62. Desmopressin (DDAVP) 63. Factor VIIa
64. Platelet Transfusion Medicine 65. Therapeutic Platelet-Rich Plasma in
Wound Healing 66. Stem Cell-Derived Platelets 67. Gene Therapy for Platelet
Disorders