A unique point-of-care guide to clinical hematology-oncology Hematology-Oncology Clinical Questions answers the questions most frequently asked by medical students or residents on rotations. The answers provided are concise, specific, evidence-based, and supported by recent references and clinical practice guidelines. Readers will find Hematology-Oncology Clinical Questions to be single-best resource for quickly translating the most current knowledge into practical, diagnostic real-time solutions. . Coverage includes both solid tumor and hematology malignancies, cancer screening and genetic…mehr
A unique point-of-care guide to clinical hematology-oncology Hematology-Oncology Clinical Questions answers the questions most frequently asked by medical students or residents on rotations. The answers provided are concise, specific, evidence-based, and supported by recent references and clinical practice guidelines. Readers will find Hematology-Oncology Clinical Questions to be single-best resource for quickly translating the most current knowledge into practical, diagnostic real-time solutions. . Coverage includes both solid tumor and hematology malignancies, cancer screening and genetic and familial cancer syndrome, supportive care and end of life, chemotherapy agents (including immunotherapy) . The content arrangement is designed to simulate the consultation process: data collection, synthesis of data, solution
Julie H. Rowe, MD; Anneliese O. Gonzalez, MD; SyedH. Jafri, MBBS.; Putao Chen, MD; Zeyad Kanaan, MD; and Robert J. Amato, DO, Adan Rios, MD, Hazem El-Osta, MD are affiliated with The University of Texas Health Scienceat Houston, McGovern Medical School.
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Table of Contents 1. CHEMOTHERAPY AGENTS -WILL INCLUDE A SUMMARY OF EACH TYPE BEFORE CLINICAL QUESTIONS a. Cytotoxic b. Targeted Agents c. Hormonal Agents d. Immunotherapy 2. RADIATION THERAPY 3. MOST COMMON HEME QUESTIONS a. Anemia b. Thrombocytopenia c. Thrombosis d. Transfusion reactions 4. SCREENING a. Breast cancer b. Cervical c. Colon Cancer d. Prostate e. Lung Cancer 5. BREAST CANCER a. Non-invasive b. Invasive c. Inflammatory breast cancer d. Phyllodes e. Paget's 6. HEAD AND NECK 7. THYROID CARCINOMAS 8. GI CANCER a. Esophagus b. Gastric/GEJ c. Colon d. Rectal e. Anus f. Pancreas g. Cholangiocarcinoma h. Hepatocellular Carcinoma i. Neuroendocrine tumors 9. GU CANCER a. Bladder b. Kidney c. Prostate d. Testicular 10. GYNECOLOGICAL MALIGNANCIES a. Cervical b. Endometrial c. Ovarian d. Uterine 11. MELANOMAS 12. THORACIC a. Small cell lung cancer b. Non-small cell lung cancer 13. SARCOMAS 14. OCCULT PRIMARY 15. BASICS OF PATHOLOGY AND HEMATOLOGY a. Bone Marrow, Flow Cytometry, Cytogenetics, Molecular testing. b. Solid tumor pathology basics 16. BASICS OF BONE MARROW TRANSPLANTATION a. Types (Allo, Auto) b. Indications 17. LYMPHOMAS a. Hodgkin's Lymphoma i. Classical HL ii. Nodular lymphocyte-predominant HL b. Non-Hodgkin's Lymphoma i. B-cell NHL a) Diffuse large B-cell Lymphoma (DLBCL) b) Follicular Lymphoma c) Mantle Cell Lymphoma (MCL) d) Small Lymphocytic Lymphoma (SLL) e) Primary CNS Lymphoma f) Primary Mediastinal Lymphoma (PML) g) Burkitt Lymphoma (BL) h) Primary Effusion Lymphoma i) Double-hit Lymphoma j) Primary Effusion Lymphoma (PEL) ii. T-Cell NHL a) Peripheral T-cell Lymphoma (PTCL) b) Primary Cutaneous T-cell Lymphoma c) Anaplastic Large Cell Lymphoma (ALCL) d) Post-Transplant Lymphoproliferative 18. LEUKEMIAS a) Acute Leukemias i. Acute Myeloid Leukemia (AML) ii. APL i. Acute Lymphoblastic Leukemia (ALL) b) Chronic Leukemias: i. Chronic Myeloid Leukemia (CML) ii. Chronic Lymphocytic Leukemia (CLL) iii. Hairy Cell Leukemia 19. PLASMA CELL DISORDERS: a. Monoclonal Gammopathy of Undetermined Significance (MGUS) b. Multiple Myeloma (MM) c. Lymphoplasmacyctic Lymphoma (including Waldenstrom's Macroglobulinemia) d. Solitary Plasmacytoma e. AL Amyloidosis f. POEMS Syndrome 20. MYELOPROLIFERATIVE NEOPLASMS a. Polycythemia Vera (PV) b. Essential Thrombocythemia (ET) c. Primary Myelofibrosis (PMF) d. Systemic Mastocytosis (SM) 21. MYELODYSPLASTIC SYNDROMES 22. GUIDELINES FOR SUPPORTIVE CARE a. Management of Side Effects of Chemotherapy i. Myelosuppression ii. Nausea iii. Vomiting iv. Diarrhea v. Mucositis vi. Anorexia, weight loss b. Management of Cancer-related pain c. Management of Cachexia 23. ONCOLOGIC EMERGENCIES a. Neutropenic Fever b. Spinal Cord Compression c. Tumor Lysis Syndrome d. Superior vena cava syndrome e. Hypercalcemia of malignancy f. Hyperleukocytosis and leukostasis 24. GENETIC AND FAMILIAL ASSESSMENT FOR FAMILIAL CANCER SYNDROMES 25. END OF LIFE
Table of Contents 1. CHEMOTHERAPY AGENTS -WILL INCLUDE A SUMMARY OF EACH TYPE BEFORE CLINICAL QUESTIONS a. Cytotoxic b. Targeted Agents c. Hormonal Agents d. Immunotherapy 2. RADIATION THERAPY 3. MOST COMMON HEME QUESTIONS a. Anemia b. Thrombocytopenia c. Thrombosis d. Transfusion reactions 4. SCREENING a. Breast cancer b. Cervical c. Colon Cancer d. Prostate e. Lung Cancer 5. BREAST CANCER a. Non-invasive b. Invasive c. Inflammatory breast cancer d. Phyllodes e. Paget's 6. HEAD AND NECK 7. THYROID CARCINOMAS 8. GI CANCER a. Esophagus b. Gastric/GEJ c. Colon d. Rectal e. Anus f. Pancreas g. Cholangiocarcinoma h. Hepatocellular Carcinoma i. Neuroendocrine tumors 9. GU CANCER a. Bladder b. Kidney c. Prostate d. Testicular 10. GYNECOLOGICAL MALIGNANCIES a. Cervical b. Endometrial c. Ovarian d. Uterine 11. MELANOMAS 12. THORACIC a. Small cell lung cancer b. Non-small cell lung cancer 13. SARCOMAS 14. OCCULT PRIMARY 15. BASICS OF PATHOLOGY AND HEMATOLOGY a. Bone Marrow, Flow Cytometry, Cytogenetics, Molecular testing. b. Solid tumor pathology basics 16. BASICS OF BONE MARROW TRANSPLANTATION a. Types (Allo, Auto) b. Indications 17. LYMPHOMAS a. Hodgkin's Lymphoma i. Classical HL ii. Nodular lymphocyte-predominant HL b. Non-Hodgkin's Lymphoma i. B-cell NHL a) Diffuse large B-cell Lymphoma (DLBCL) b) Follicular Lymphoma c) Mantle Cell Lymphoma (MCL) d) Small Lymphocytic Lymphoma (SLL) e) Primary CNS Lymphoma f) Primary Mediastinal Lymphoma (PML) g) Burkitt Lymphoma (BL) h) Primary Effusion Lymphoma i) Double-hit Lymphoma j) Primary Effusion Lymphoma (PEL) ii. T-Cell NHL a) Peripheral T-cell Lymphoma (PTCL) b) Primary Cutaneous T-cell Lymphoma c) Anaplastic Large Cell Lymphoma (ALCL) d) Post-Transplant Lymphoproliferative 18. LEUKEMIAS a) Acute Leukemias i. Acute Myeloid Leukemia (AML) ii. APL i. Acute Lymphoblastic Leukemia (ALL) b) Chronic Leukemias: i. Chronic Myeloid Leukemia (CML) ii. Chronic Lymphocytic Leukemia (CLL) iii. Hairy Cell Leukemia 19. PLASMA CELL DISORDERS: a. Monoclonal Gammopathy of Undetermined Significance (MGUS) b. Multiple Myeloma (MM) c. Lymphoplasmacyctic Lymphoma (including Waldenstrom's Macroglobulinemia) d. Solitary Plasmacytoma e. AL Amyloidosis f. POEMS Syndrome 20. MYELOPROLIFERATIVE NEOPLASMS a. Polycythemia Vera (PV) b. Essential Thrombocythemia (ET) c. Primary Myelofibrosis (PMF) d. Systemic Mastocytosis (SM) 21. MYELODYSPLASTIC SYNDROMES 22. GUIDELINES FOR SUPPORTIVE CARE a. Management of Side Effects of Chemotherapy i. Myelosuppression ii. Nausea iii. Vomiting iv. Diarrhea v. Mucositis vi. Anorexia, weight loss b. Management of Cancer-related pain c. Management of Cachexia 23. ONCOLOGIC EMERGENCIES a. Neutropenic Fever b. Spinal Cord Compression c. Tumor Lysis Syndrome d. Superior vena cava syndrome e. Hypercalcemia of malignancy f. Hyperleukocytosis and leukostasis 24. GENETIC AND FAMILIAL ASSESSMENT FOR FAMILIAL CANCER SYNDROMES 25. END OF LIFE
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