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This book brings together in one volume recent knowledge of mechanisms which determines the ability of the gastrointestinal tract to withstand damage that potentially may be aimed against it. Also, the use of feed additives and probiotics as alternatives to antibiotics as growth promoters, safety aspects on non-use of antibiotics, as well as the current status of the use of antibiotics and probiotics in the EU is discussed. With an increasing awareness of the human health risks of the regular use of feed antibiotics as growth promoters in animal production, these techniques have been questioned. However, in order to make a change in production model possible, more knowledge is needed on alternative ways for the prevention of health problems in pigs. The underlying science related to this area is highlighted.