Dosage Form Design Parameters

Volume II

• Gebundenes Buch

Produktbeschreibung

Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries.

Produktdetails

• Advances in Pharmaceutical Product Development and Research
• Verlag: Elsevier Science Publishing Co Inc
• Seitenzahl: 810
• Erscheinungstermin: 10. August 2018
• Englisch
• Abmessung: 198mm x 242mm x 50mm
• Gewicht: 1778g
• ISBN-13: 9780128144213
• ISBN-10: 0128144211
• Artikelnr.: 49670332

Inhaltsangabe

1. Levels of solid state properties: Role of different levels during
pharmaceutical development 2. Polymorphism and its Implications in
Pharmaceutical Product Development 3. Basics of crystallization process
applied in drug research 4. Role of amorphous state in drug delivery 5.
Particulate level properties and its implications on product performance
and processing 6. Bulk level properties and its role in formulation
development and processing 7. Concepts of hypothesis testing and types of
errors 8. Experimental design and analysis of variance 9. Basic concept and
application of Sampling procedures 10. Statistical techniques in
Pharmaceutical Product Development 11. Drug-excipient interaction and
incompatibilities 12. Documentation protocols in product development
department including clinical records 13. Correlation between in-vitro and
in-vivo screens: Special emphasis on high throughput screening, high
throughput pharmacokinetic analysis 14. Sterilization of pharmaceuticals:
Technology, Equipment and Validation 15. Package development of
pharmaceutical products: Aspects of packaging materials used for
Pharmaceutical Products 16. Package types for different dosage forms 17.
Food and drug laws effecting pharmaceutical product design, development and
commercial manufacturing 18. Guiding Principles for Human and Animal
Research during pharmaceutical product development 19. Applications of
Computer in Pharmaceutical Product Development 20. Patents and other
intellectual property rights in drug delivery 21. Computer Aided Prediction
of Pharmacokinetic (ADMET) Properties 22. Ethics and Legal Protection of
Uses of Computer Applications in Pharmaceutical Research