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Colorectal cancer (CRC) remains a public health issue in developed countries, occupying the third and fourth positions in the frequency of neoplastic diseases locations. The high rate of complete curing of the disease compared to other malignancies, is depending on an early diagnosis. The existence of preceding benign lesions has a role of "signal" lesions in detecting the area on which the colorectal neoplasm will develop. In over 90% of the cases, the colorectal neoplastic lesion has as lesion substratum a pre-existing benign lesion of "polyploidy" form. The therapeutic attitude is dominated…mehr

Produktbeschreibung
Colorectal cancer (CRC) remains a public health issue in developed countries, occupying the third and fourth positions in the frequency of neoplastic diseases locations. The high rate of complete curing of the disease compared to other malignancies, is depending on an early diagnosis. The existence of preceding benign lesions has a role of "signal" lesions in detecting the area on which the colorectal neoplasm will develop. In over 90% of the cases, the colorectal neoplastic lesion has as lesion substratum a pre-existing benign lesion of "polyploidy" form. The therapeutic attitude is dominated by endoscopy coupled with histopathological exam in various technical variants. Given the high frequency of CRC and the epidemiologically demonstrated relationships with polyps or colorectal polyposis, it would be desirable for these pathologies to be included in national programs for screening and therapy.
Autorenporträt
Alexandra BOLOCAN, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. Postdoctoral fellow of Research Institute of the University of Bucharest, Romania. Editor of Biomaterials and Tissue Engineering Bulletin, edited by M.R. Hamblin (Harvard Medical School, USA) and by A.M. Grumezescu (University Politehnica of Bucharest, RO).