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This book translates fundamental knowledge in basic cardiac electrophysiology from the bench to the bedside. Revised and updated for its second edition, the text offers new coverage of the molecular mechanisms of ion channel behavior and its regulation, complex arrhythmias, and the broadening roles of devices and ablation. Clear, straightforward explanations are illustrated by plentiful diagrams to make the material accessible to the non-specialist.
This book translates fundamental knowledge in basic cardiac electrophysiology from the bench to the bedside. Revised and updated for its second edition, the text offers new coverage of the molecular mechanisms of ion channel behavior and its regulation, complex arrhythmias, and the broadening roles of devices and ablation. Clear, straightforward explanations are illustrated by plentiful diagrams to make the material accessible to the non-specialist.
José Jalife, M.D., F.A.C.C., F.H.R.S. Professor and Chairman of Pharmacology Professor of Medicine and Pediatrics Director, Institute for Cardiovascular Research SUNY Upstate Medical University Syracuse, NY Mario Delmar, M.D., Ph.D., F.H.R.S. Professor of Pharmacology Co-Director, Institute for Cardiovascular Research SUNY Upstate Medical University Syracuse, NY Justus Anumonwo, Ph.D. Assistant Professor of Pharmacology Member, Institute for Cardiovascular Research SUNY Upstate Medical University Syracuse, NY Omer Berenfeld Jerome Kalifa
Inhaltsangabe
Acknowledgments, vii Foreword to the Second Edition by Douglas P. Zipes, ix Foreword to the First Edition by Douglas P. Zipes, xi Introduction, 1 Chapter 1 Bioelectricity, 7 Chapter 2 Ion Channels, 43 Chapter 3 Ion Channel Regulation, 72 Chapter 4 Impulse Initiation and Propagation in Cardiac Muscle, 92 Chapter 5 Rate Dependency of Discontinuous Propagation, 121 Chapter 6 Basic Mechanisms of Cardiac Arrhythmias, 152 Chapter 7 Rotors, Spirals, and Scroll Waves in the Heart, 191 Chapter 8 Rotors and the Mechanisms of Atrial Fibrillation, 224 Chapter 9 Molecular Mechanisms of Ventricular Fibrillation, 254 Chapter 10 Inheritable Arrhythmogenic Diseases, 276 Bibliography, 316 Index, 335
Provisional Table of Contents. Chapter 1. Principles of Bioelectricity. Chapter 2. Ion Channels. Chapter 3. Ion Channel Regulation. Chapter 4. Pacemaker Synchronization. Chapter 5. Propagation in Cardiac Muscle. Chapter 6. Rate Dependency of Discontinuous Propagation. Chapter 7. Basic Mechanisms of Cardiac Arrhythmias. Chapter 8. Inherited and acquired Ion Channel Diseases. Chapter 9. Rotors and the Mechanisms of Atrial Fibrillation. Chapter 10. Molecular Mechanisms of Ventricular Fibrillation
Acknowledgments, vii Foreword to the Second Edition by Douglas P. Zipes, ix Foreword to the First Edition by Douglas P. Zipes, xi Introduction, 1 Chapter 1 Bioelectricity, 7 Chapter 2 Ion Channels, 43 Chapter 3 Ion Channel Regulation, 72 Chapter 4 Impulse Initiation and Propagation in Cardiac Muscle, 92 Chapter 5 Rate Dependency of Discontinuous Propagation, 121 Chapter 6 Basic Mechanisms of Cardiac Arrhythmias, 152 Chapter 7 Rotors, Spirals, and Scroll Waves in the Heart, 191 Chapter 8 Rotors and the Mechanisms of Atrial Fibrillation, 224 Chapter 9 Molecular Mechanisms of Ventricular Fibrillation, 254 Chapter 10 Inheritable Arrhythmogenic Diseases, 276 Bibliography, 316 Index, 335
Provisional Table of Contents. Chapter 1. Principles of Bioelectricity. Chapter 2. Ion Channels. Chapter 3. Ion Channel Regulation. Chapter 4. Pacemaker Synchronization. Chapter 5. Propagation in Cardiac Muscle. Chapter 6. Rate Dependency of Discontinuous Propagation. Chapter 7. Basic Mechanisms of Cardiac Arrhythmias. Chapter 8. Inherited and acquired Ion Channel Diseases. Chapter 9. Rotors and the Mechanisms of Atrial Fibrillation. Chapter 10. Molecular Mechanisms of Ventricular Fibrillation
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