Farshid Guilak / David L. Butler / Steven A. Goldstein / David Mooney (eds.)

Functional Tissue Engineering

Ed. by Farshid Guilak, David L. Butler, Steven A. Goldstein et al.

• Broschiertes Buch

Produktbeschreibung

-Softcover reprint of a successful hardcover reference (370 copies sold)
-Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering
-Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology

Produktdetails

• Verlag: Springer, Berlin
• Artikelnr. des Verlages: 10983584
• 2003
• Seitenzahl: 444
• Erscheinungstermin: 25. August 2004
• Englisch
• Abmessung: 254mm x 178mm x 24mm
• Gewicht: 800g
• ISBN-13: 9780387220130
• ISBN-10: 0387220135
• Artikelnr.: 14767020

Autorenporträt

Farshid Guilak, Duke University Medical Center, Durham, NC, USA / David L. Butler, University of Cincinnati, OH, USA / Steven A. Goldstein, University of Michigan, Ann Arbor, MI, USA / David Mooney, University of Michigan, Ann Arbor, MI, USA

Inhaltsangabe

From the contents: I. The Functional Properties of Native Tissues.- II. Functional Requirements of Engineered Tissues.- III. Design Parameters for Tissue Engineering.- IV. Assessment of Function in Engineered Tissues.- V. Cell-matrix Interactions in Functional Tissue Engineering.- VI. Bioreactors and the Role of Biophysical Stimuli in Tissue Engineering.- VII. Regulatory and Clinical Issues in Tissue Engineering.

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Part I. The Functional Properties of Native Tissues * How Does Nature Build a Tissue? * Ligament Healing: Present Status and the Future of Functional Tissue Engineering * Native Properties of Cardiovascular Tissues: Guidelines for Functional Tissue Engineering * Functional Properties of Native Articular Cartilage * Excitability and Contractility of Skeletal Muscle: Measurements and Interpretations * Part II. Functional Requirements of Engineered Tissues * Functional Requirements for the Engineering of a Blood Vessel Substitute * In vivo Force and Strain of Tendon, Ligament and Capsule * Requirements for Biological Replacement of the Articular Cartilage at the Knee Joint * Functional Requirements: Cartilage * Part III. Design Parameters for Tissue Engineering * Design Parameters for Functional Tissue Engineering * Tissue Engineering a Heart: Critical Issues * Design Parameters for Engineering Bone Regeneration * Tissue Engineering of Bone: The Potential Uses of Gene Therapy for Difficult Bone Loss Problems * Engineered Skeletal Muscle: Functional Tissues, Organs and Interfaces * Bioengineering the Growth of Articular Cartilage * Part IV. Assessment of Function in Engineered Tissues * Functional Tissue Engineering: Assessment of Function in Tendon and Ligament Repair * The Role of Mechanical Forces in Tissue Engineering of Articular Cartilage * Biomechanics of Native and Engineered Heart Valves * Assessment of Function in Tissue Engineered Vascular Grafts * Assessment of the Performance of Engineered Tissues in Humans Requires the Development of Highly Sensitive and Quantitative Non-invasive Outcome Measures * Part V. Cell-matrix Interactions in Functional Tissue Engineering * The Biomechanics of Cell-matrix Interactions in Tissue Engineering * Regulation of Cellular Response to Mechanical Signals by Matrix Design * Artificial Soft Tissue Fabrication from Cell-contracted Biopolymers * Cytomechanics: Signaling to Mechanical Load in Connective Tissue Cells and Role in Tissue Engineering * Part VI. Bioreactors and the Role of Biophysical Stimuli in Tissue Engineering * The Role of Biomechanics in Analysis of Cardiovascular Diseases: Regulation of the Fluid Shear Response by Inflammatory Mediators * A Full Spectrum of Tissue Engineered Blood Vessels: From Macroscopic to Microscopic * Engineered Functional Cartilage and Cardiac Tissue: In vitro Culture Parameters * Tissue Engineered Skeletal Muscle * Part VII. Regulatory and Clinical Issues in Tissue Engineering * From Concept Towards the Clinic: Preclinical Evaluation of Tissue Engineered Constructs * Trends in the FDA

Rezensionen

From the reviews:

"Functional Tissue Engineering is a useful compilation of research by contributors involved in developing tissues ... . It is not easy to extract a decent book from a conference, but the editors have done a very good job ... . it will be an invaluable source for those starting a PhD ... . I recommend it to those embarking on or already involved in engineering structural tissues. ... The chapters are well written ... . The book is clearly focused to encompass practical issues, such as the need to create appropriate biomechanical environments ... ." (Sheila MacNeil, Materials Today, July/August, 2005)