This book highlights the latest breakthrough developments in bioinformatics. It presents a series of timely, in-depth reviews, drug clinical trial studies, biodiversity informatics and thematic issues. In addition, it includes insightful reviews on advances in computational molecular/structural biology, which address areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. Innovations in these fields have direct impacts on key issues related to healthcare, medicine, genetic disorders, the development of agricultural…mehr
This book highlights the latest breakthrough developments in bioinformatics. It presents a series of timely, in-depth reviews, drug clinical trial studies, biodiversity informatics and thematic issues. In addition, it includes insightful reviews on advances in computational molecular/structural biology, which address areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. Innovations in these fields have direct impacts on key issues related to healthcare, medicine, genetic disorders, the development of agricultural products, renewable energy, and environmental protection.
Written by respected leaders in the field and covering a wide range of topics involving the integration of biology with computer and information science, the book offers an ideal basis for teaching at the undergraduate and graduate levels. It can also be used for self-instruction by research investigators interested in applying bioinformatics-based analytical methods and information technologists working with academic and industrial laboratories.
Dr. Gulshan Wadhwa is currently the Joint Director in the Department of Biotechnology, Ministry of Science & Technology, Government of India. He has developed the Bioinformatics program in India (BTISnet) and established teaching & training programmes and a super computing facility in Bioinformatics in India. He has undergone trainings from WIPO, Geneva and NUS, Singapore. Dr. Jayesh R. Bellare is currently Institute chair Professor and Professor with Chemical Engineering department & Center for Research in NanoTechnology and Science, Indian Institute of Technology-Bombay, Mumbai, India. He was a Post Doctoral Fellow, from M.I.T., Cambridge, USA and has over 33 years of experience. Dr. P. Shanmughavel is currently working as Associate Professor at Bharathiar University, Coimbatore, India. He has published 7 books in bioinformatics (two books published in Germany), 6 book chapters, 5 conference proceedings and 31 research papers in the reputed National and International journals in Bioinformatics. He has established the Centre of Bioinformatics-"DBT-BIF" in 2006. Dr. Atul Kumar Singh is currently working as Senior Scientist at Indian Institute of Technology-Delhi. He has completed his Doctorate from Indian Institute of Technology-Bombay, Mumbai in Nanotechnology. He has published 11 research papers in the reputed International journals and has 6 patents.
Part 1. Overview.- Chapter 1. An Insight of Biological Databases used in Bioinformatics.- Chapter 2- Bioinformatics in Next-Generation Genome Sequencing.- Chapter 3. The Role of Bioinformatics in Epigenetics.- Chapter 4. Three dimensional structures of carbohydrates and glycoinformatics - An Overview.- Chapter 5. Epigenome: The guide to Genomic Expression.- Part 2. Bioinformatics Approaches.- Chapter 6. Molecular Modeling and Drug Design: A Contemporary Analysis in Vibrio cholera .- Chapter 7. Modelling Polyketide Synthases and Similar Macromolecular Complexes.- Chapter 8. In silico Studies on Colon Cancer.- Chapter 9. Tools, Databases and Applications of Immunoinformatics.- Chapter 10. Metabolic Pathway Analysis Employing Bioinformatics Software.- Chapter 11. The Interactomics of the RNA Induced Silencing Complex.- Chapter 12. Computational Tools: RNA Interference in Fungal Therapeutics.- Chapter 13. Genome Wide Essential Gene Identification in Pathogens.- Chapter 14. Disease Informatics.- Chapter 15- Development in Malaria and Anemia Screening: Medical Imaging Informatics Approach.- Chapter 16. Role of Bioinformatics in Drug-Resistance Prediction forHIV/AIDS.- Chapter 17. Bioinformatics approaches for animal breeding and genetics.- Chapter 18. -Amylase Inhibitor's performancein the Control of Diabetes Mellitus: Anapplication of computational Biology.
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