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A broad overview of the interaction of DNA with surfactants andpolymers Due to the potential benefits of biotechnology, interest in theinteraction between DNA and surfactants and polymers has becomeincreasingly significant. Now, DNA Interactions with Polymersand Surfactants provides an extensive, up-to-date overview ofthe subject, giving readers a basis for understanding the factorsleading to complexation between DNA and different cosolutes,including metal ions, polyelectrolytes, spermine, spermidine,surfactants and lipids, and proteins. Topical coverage includes: * Polyelectrolytes,…mehr

Produktbeschreibung
A broad overview of the interaction of DNA with surfactants andpolymers Due to the potential benefits of biotechnology, interest in theinteraction between DNA and surfactants and polymers has becomeincreasingly significant. Now, DNA Interactions with Polymersand Surfactants provides an extensive, up-to-date overview ofthe subject, giving readers a basis for understanding the factorsleading to complexation between DNA and different cosolutes,including metal ions, polyelectrolytes, spermine, spermidine,surfactants and lipids, and proteins. Topical coverage includes: * Polyelectrolytes, physico-chemical aspects and biologicalsignificance * Solution behavior of nucleic acids * Single DNA molecules: compaction and decompaction * Interaction of DNA with surfactants and cationic polymers * Interactions of histones with DNA * DNA-DNA interactions * The hydration of DNA-amphiphile complexes * DNA-surfactant/lipid complexes at liquid interfaces * DNA and DNA-surfactant complexes at solid surfaces * The role of correlation forces for DNA-cosolute interactions * Simulations of polyions * Cross-linked DNA gels and gel particles * DNA as an amphiphilic polymer * Lipid-DNA interactions Covering both theoretical and practical aspects of the subject,DNA Interactions with Polymers and Surfactants is an idealresource for chemists and biochemists working in gene and DNAdelivery research in industry and academia, as well as for cellbiologists, chemical engineers, molecular biologists, anddevelopment biologists in the pharmaceutical industry.

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  • Produktdetails
  • Verlag: John Wiley & Sons
  • Seitenzahl: 550
  • Erscheinungstermin: 03.07.2008
  • Englisch
  • ISBN-13: 9780470286357
  • Artikelnr.: 37291519
Autorenporträt
Rita S. Dias, PhD, is a postdoctoral scientist in theDepartment of Physical Chemistry at Lund University, Sweden. Hercurrent research involves the control of DNA condensation usingsurfactant mixtures and Monte Carlo simulations on the compactionof DNA and interaction of macromolecules with coarse-grained lipidmembranes. Björn Lindman, PhD, has served as Full Professor atLund University for the past three decades. Dr. Lindman'scontributions have included the determination of the structure ofmicroemulsions, the development of novel delivery systems forpharmaceuticals, and new systems for eliminating adhesions insurgery. He was the first to establish phase diagrams for mixedpolymer-surfactant solutions as well as the bicontinuity ofmicroemulsions. Dr. Lindman is the author of hundreds of scientificpublications and has coauthored or edited several books, includingSurfactants and Polymers in Aqueous Solution, Second Edition(Wiley).
Inhaltsangabe
Preface.
Contributors.
1 Polyelectrolytes. Physicochemical Aspects and Biological Significance (Magnus Ullner).
References.
2 Solution Behavior of Nucleic Acids (Rita S. Dias).
Acknowledgments.
References.
3 Single DNA Molecules: Compaction and Decompaction (Anatoly A. Zinchenko, Olga A. Pyshkina, Andrey V. Lezov, Vladimir G. Sergeyev, and Kenichi Yoshikawa).
References.
4 Interaction of DNA with Surfactants in Solution (Rita S. Dias, Kenneth Dawson, and Maria G. Miguel).
Acknowledgments.
References.
5 Interaction of DNA with Cationic Polymers (Eric Raspaud, Adriana C. Toma, Francoise Livolant, and Joachim Radler).
Acknowledgment.
References.
6 Interactions of Histones with DNA: Nucleosome Assembly, Stability, Dynamics, and Higher Order Structure (Karsten Rippe, Jacek Mazurkiewicz, and Nick Kepper).Acknowledgments.
References.
7 Opening and Closing DNA: Theories on the Nucleosome (Igor M. Kulic and Helmut Schiessel).
Acknowledgment.
References.
8 DNA-DNA Interactions (Lars Nordenskiöld, Nikolay Korolev, and Alexander P. Lyubartsev).
References.
9 Hydration of DNA-Amphiphile Complexes (Cecilia Leal and Hakan Wennerstrom).
References.
10 DNA-Surfactant/Lipid Complexes at Liquid Interfaces (Dominique Langevin).
References 286
11 DNA and DNA-Surfactant Complexes at Solid Surfaces (Marite Cardenas and Tommy Nylander).
Acknowledgments.
References.
12 Role of Correlation Forces for DNA-Cosolute Interactions (Malek O. Khan).
References.
13 Simulations of Polyions: Compaction, Adsorption onto Surfaces, and Confinement (A.A.C.C. Pais and P. Linse).
References.
14 Cross-linked DNA Gels and Gel Particles (Diana Costa, M. Carmen Moran, Maria G. Miguel, and Bjorn Lindman)
References.
15 DNA as an Amphiphilic Polymer (Rita S. Dias, Maria G. Miguel, and Bjorn Lindman).
References.
16 Lipid-DNA Interactions: Structure-Function Studies of Nanomaterials for Gene Delivery (Kai K. Ewert, Charles E. Samuel, and Cyrus R. Safinya).
Acknowledgments.
References.
Index.
Rezensionen
"Aims to give readers an overview of the subject and a basis for understanding the factors leading to the complexation between DNA and different co-salutes." (TCE - The Chemical Engineer, July 2008)