Esther Asan

The Catecholaminergic Innervation of the Rat Amygdala (eBook, PDF)

• Format: PDF

Produktbeschreibung

Experimental evidence indicates that catecholamines are able to modulate information processing in the amygdaloid complex. The dense catecholaminergic innervation of the amygdala may thus exert significant influence upon its well-documented functions in emotion, attention, learning and memory. Dysfunctions of the systems have been suggested to be involved in the etiology of neuropsychiatric disorders including senile dementia, Parkinson's disease and schizophrenia. To further insight into neural mechanisms of the innervation, the present study provides a detailed documentation of ultrastructural and neurochemical characteristics of dopanminergic, noradrinergic and adrenergic afferent fibers and of their target structures in central, basal and intercalated amygdaloid nuclei. A high degree of heterogeneitiy is observed between the nuclei concerning the different catecholaminergic innervation patterns and the peptide content of individual catecholaminergic fibers, as well as concerning the neurotransmitter/-modulator and receptor expression of possible amygdaloid target neurons. The results are discussed with regard to previously documented properties of the nuclei.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 121
• Erscheinungstermin: 12. März 2013
• Englisch
• ISBN-13: 9783642720857
• Artikelnr.: 53201518

Autorenporträt

Experimental evidence indicated that catecholamines are able to modulate information processing in the amygdaloid complex. The present study provides a detailed documentation of ultrastructural and neurochmical characteristics of dopaminergic, noradrinergic, and adrenergic afferent fibers and of their target structures in central, basal and intercalated amygdaloid nuclei.

Inhaltsangabe

1 Introduction.- 2 Materials and Methods.- 2.1 Tissue Preparation.- 2.2 Immunocytochemistry.- 2.3 In Situ Hybridization.- 3 Results and Discussions.- 3.1 Cytoarchitectonics.- 3.2 Comparative Light, Fluorescence, and Electron-Microscopic Studies of the Morphology and Neurochemistry of Catecholaminergic Afferent Fibers to the Amygdala.- 3.2.3 Conclusions for the Identification of Dopaminergic, Noradrenergic, and Adrenergic Structures.- 3.3 Ultrastructural Features of Neurons and Catecholaminergic Afferent Fibers in the Nucleus Centralis, the Basal Complex, and the Paracapsular Intercalated Cell Groups.- 3.4 Colocalization of Neuropeptides in Catecholaminergic Afferent Fibers to the Amygdala.- 3.5 Neurochemical Characterization of Possible Target Neurons of the Catecholaminergic Amygdala Innervation.- 4 Summary.- 4.1 Conclusions for the Individual Amygdaloid Nuclei.- 4.2 Conclusions for the Different Types of Catecholaminergic Innervation.- 5 References.