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Industrial Scale Suspension Culture of Living Cells (eBook, PDF)
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Comprehensive and comparative coverage of all suspension cell-based production methods, containing outstanding contributions from a balanced mix of industry and academia, and edited by leading figures at one of the largest companies using industrial-scale biotechnology processing. All chapters adhere to a standardized structure and the editors have carefully avoided any overlaps in content. The following are included for each host or expression system presented: (a) organisms, cells, expression systems, products, (b) basic process design aspects, (c) basic bioreactor design aspects, (d) key…mehr

Produktbeschreibung
Comprehensive and comparative coverage of all suspension cell-based production methods, containing outstanding contributions from a balanced mix of industry and academia, and edited by leading figures at one of the largest companies using industrial-scale biotechnology processing. All chapters adhere to a standardized structure and the editors have carefully avoided any overlaps in content. The following are included for each host or expression system presented: (a) organisms, cells, expression systems, products, (b) basic process design aspects, (c) basic bioreactor design aspects, (d) key factors affecting process economics, (e) regulatory aspects, (f) summary and outlook.
Autorenporträt
The holder of a PhD in microbiology from the University of Fribourg, Switzerland, Hans-Peter Meyer served as VP Strategic Projects Biotechnology at Lonza until his retirement in early 2014. Following three years of postdoctoral studies in Stockholm, at the University of Pennsylvania, Philadelphia, and Lehigh University, Bethlehem, USA, in 1982 he joined Prof. Armin Fiechter's team as group leader at the ETH in Zürich before starting at Lonza in Visp, Switzerland in 1986, where he held a number of positions in R&D, manufacturing, and sales & marketing. He recently joined the faculty of the University of Applied Sciences and Arts of Western Switzerland, and also remains an expert at the Commission for Technology & Innovation (CTI) of the Swiss Federal Confederation. Diego R. Schmidhalter is head of R&T within the pharma and biotechnology custom manufacturing division at Lonza Switzerland. He holds a PhD in microbiology from the University of Fribourg, Switzerland, and carried out two years of postdoctoral studies at Genencor International, California, USA. He has held various management positions at Lonza, including head of microbial anufacturing, head of the Biopharma R&D Services business, and as head of Microbial Manufacturing Science and Technology, as well as being a member of the Biopharmaceuticals business team. Dr. Schmidhalter has over 20 years of experience in the biotechnology industry in biopharmaceuticals and biochemicals process development and manufacturing, technology transfer, scaling-up fermentations right up to the 50,000-liter scale, and within the biopharmaceuticals related regulatory environment.