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The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance…mehr

Produktbeschreibung
The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GB, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

  • Produktdetails
  • Verlag: Springer-Verlag GmbH
  • Erscheinungstermin: 13.08.2013
  • Englisch
  • ISBN-13: 9789400762114
  • Artikelnr.: 43788385
Inhaltsangabe
PART I Molecular Bases for Stem and Cancer Cells Proliferation 1 An introduction to proliferation and migration of stem cells and cancer Micheli Mainardi Pillat, Talita Glaser, Telma Tiemi Schwindt and Henning Ulrich 2 The role of cell adhesions, cell junctions and extracellular matrix in normal development and carcinogenesis Anderson K. Santos, Fernanda M. P. Tonelli, Daniel A. F. Silva, Kátia N. Gomes, Luiz O. Ladeira and Rodrigo R. Resende 3 The embryonic rest hypothesis of cancer development:150 years later Mariusz Z. Ratajczak, Maciej Tarnowski, Sylwia Borkowska, Karol Serwin . 4 Are calcium channels more important than calcium influx for cell proliferation ? Anne-Sophie Borowiec, Gabriel Bidaux and Thierry Capiod 5 Role of calcium signaling in stem cells and cancer cells proliferation Maria Jimena Amaya, Vânia A. M. Goulart, Anderson K. Santos, Alexandre H. Kihara, Silvia Guatimosim, Rodrigo R. Resende . 6 Formation and function of lipid droplets in inflammation and cancer João P.B. Viola, André L.S. Cruz, Miriam B.F. Werneck, Patricia T. Bozza 7 The role of sphingolipids in modulating pluripotency of stem cells Salman B. Hosain, Ronald A. Hill, Yong-Yu Liu PART II Signaling Pathways to Cancer Cells Fate 8 Signaling pathways of cbl-b and its role on peripheral t cell tolerance K Venuprasad 9 BH3-only proteins in cancer and apoptosis Fabio Ghiotto, Claudya Tenca, Franco Fais and Silvia Bruno 10 Signaling pathways of mta family proteins as regulators of cancer progression and metastasis Yasushi Toh, Garth L. Nicolson 11 Signalling pathways of beta-catenin/jnk on carcinogenesis Eliana Kalakouti, Roya Babaei-Jadidi and Abdolrahman S. Nateri 12 The regulation of the jnk cascade and programmed cell death by nf-b: mechanisms and functions Jason Bennett, Marta Moretti, Anil K. Thotakura, Laura Tornatore and Guido Franzoso PART III Uncontrolled Physiology Process Guiding to Cancer Cells 13 Migration, metastasis and more: the role of chemokines in the proliferation, spreading and metastasis of tumors Rolf Mentlein, Kirsten Hattermann and Janka Held-Feindt 14 Autophagy, cell death, and cancer Maryam Mehrpour, Ahmed Hamaï and Patrice Codogno 15 The duality of stem cells - double edged sword in tumour evolution and treatment Urska Tajnsek, Helena Motaln, Natasa Levicar , Ana Rotter and Tamara T.Lah 16 Glioblastoma stem cells and implications for chemoresistance Suzana A. Kahn, Ema Torrado, Dora Brites, Vivaldo Moura Neto 17 The tumor microenvironment as a transient niche: a modulator of epigenetic states and stem cell functions Lorena E. Mora-Blanco, James B. Lorens, and Mark A. LaBarge 18 Tumor-associated neutrophils (tans) André Gustavo Oliveira, Rodrigo Guabiraba, Mauro Martins Teixeira and Gustavo Batista Menezes 19 MicroRNA control of apoptotic programs in cancer Reena V. Kartha and Subbaya Subramanian PART IV Therapeutic Strategies for Anticancer Treatment 20 Markers of cancer stem cells and their functions Olivier Gires 21 Cancer cell dormancy: potential therapeutic targets to eradicate cancer cells within the niche Jessian L.Munoz, Jacqueline M. Park, Sarah A. Bliss, Pranela Rameshwar 22 Modulating apoptosis in cancer therapy with ultrasound and high intensity nanosecond electric pulses Tinghe Yu, Minghe Wu, Ping Huang, Lina Hu 23 Targeting cell cycle for anticancer treatment and neuroprotection Yun Dai, Shuang Chen, Liang Yi, Minhui Xu