Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides…mehr
Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
Chapter 2 Classical and Atypical Scrapie in Sheep and Goats Christine Fast, Martin H. Groschup
Chapter 3 Chronic wasting disease and the development of research models Glenn Telling
Chapter 4 Sporadic Human Prion Disease Pierluigi Gambetti
Chapter 5 Environmentally-acquired Transmissible Spongiform Encephalopathy Paul Brown
Chapter 6 Prions in the Environment Shannon L. Bartelt-Hunt, Jason C. Bartz, Samuel E. Saunders
Chapter 7 The Spectrum of Tau Pathology in Human Prion Disease Gabor G. Kovacs, Herbert Budka
Chapter 8 Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion Alexander H. Peden, Mark W. Head, James W. Ironside
Chapter 9 Species Barriers in Prion Disease Suzette A. Priola
Chapter 10 Transgenic Mice Modelling Abigail B. Diack, Rona Wilson, Enrico Cancellotti, Barry Bradford, Matthew Bishop, Jean C. Manson
Chapter 11 Prion Transmission Studies in Transgenic Mice Qingzhong Kong
Chapter 12 Alternative Models of Prion Diseases Pedro Fernandez-Funez, Edward Málaga-Trillo, Diego E. Rincon-Limas
Chapter 13 Diagnosis of Prion Disease: Conventional Approaches Inga Zerr, Joanna Gawinecka, Katharina Stoeck, Maren Breithaupt
Chapter 14 Quaking-induced Conversion (QuIC) Assays for the Detection and Diagnosis of Prion Diseases Jason M. Wilham, Christina D. Orrù, Sarah Vascellari, Andrew G. Hughson, Byron Caughey
Chapter 15 The Tyr-Tyr-Arg Prion-Specific Epitope: Update and Context T. Dean Airey, and Neil R. Cashman
Chapter 16 Overview on Treatment of Prion Diseases and Decontamination of Prions Richard Knight
Chapter 17 Immunomodulation Thomas Wisniewski, Fernando Goñi
Chapter 2 Classical and Atypical Scrapie in Sheep and Goats Christine Fast, Martin H. Groschup
Chapter 3 Chronic wasting disease and the development of research models Glenn Telling
Chapter 4 Sporadic Human Prion Disease Pierluigi Gambetti
Chapter 5 Environmentally-acquired Transmissible Spongiform Encephalopathy Paul Brown
Chapter 6 Prions in the Environment Shannon L. Bartelt-Hunt, Jason C. Bartz, Samuel E. Saunders
Chapter 7 The Spectrum of Tau Pathology in Human Prion Disease Gabor G. Kovacs, Herbert Budka
Chapter 8 Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion Alexander H. Peden, Mark W. Head, James W. Ironside
Chapter 9 Species Barriers in Prion Disease Suzette A. Priola
Chapter 10 Transgenic Mice Modelling Abigail B. Diack, Rona Wilson, Enrico Cancellotti, Barry Bradford, Matthew Bishop, Jean C. Manson
Chapter 11 Prion Transmission Studies in Transgenic Mice Qingzhong Kong
Chapter 12 Alternative Models of Prion Diseases Pedro Fernandez-Funez, Edward Málaga-Trillo, Diego E. Rincon-Limas
Chapter 13 Diagnosis of Prion Disease: Conventional Approaches Inga Zerr, Joanna Gawinecka, Katharina Stoeck, Maren Breithaupt
Chapter 14 Quaking-induced Conversion (QuIC) Assays for the Detection and Diagnosis of Prion Diseases Jason M. Wilham, Christina D. Orrù, Sarah Vascellari, Andrew G. Hughson, Byron Caughey
Chapter 15 The Tyr-Tyr-Arg Prion-Specific Epitope: Update and Context T. Dean Airey, and Neil R. Cashman
Chapter 16 Overview on Treatment of Prion Diseases and Decontamination of Prions Richard Knight
Chapter 17 Immunomodulation Thomas Wisniewski, Fernando Goñi
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