Stuart Warren, Paul Wyatt

Organic Synthesis

The Disconnection Approach

• Gebundenes Buch

Produktbeschreibung

Organic Synthesis: The Disconnection Approach is the long-awaited second edition of a classic textbook; the first to provide a structured course in retrosynthesis- now an important technique used by generations of organic chemists. Now fully revised and updated with a modern look, 25 years of advances in organic synthesis are reflected with the addition of new examples and synthetic pathways. Additional material has been added to take the student to the level required by the bestselling sequel, "Organic Synthesis: Strategy and Control" and the later chapters have extensive new material based on courses that the authors give to chemists in the pharmaceutical industry.

Produktdetails

• Verlag: John Wiley & Sons / Open Stax Textbooks
• 2nd edition
• Seitenzahl: 352
• Erscheinungstermin: 31. Dezember 2008
• Englisch
• Abmessung: 254mm x 195mm x 29mm
• Gewicht: 897g
• ISBN-13: 9780470712375
• ISBN-10: 0470712376
• Artikelnr.: 26106429

Autorenporträt

Dr Stuart Warren, Department of Chemistry, University of Cambridge, UK Dr Warren is the author of the bestselling textbooks Organic Synthesis: The Disconnection Approach (Wiley), Organic Synthesis: Strategy and Control (Wiley) and Organic Chemistry (OUP). Dr Paul Wyatt, School of Chemistry, University of Bristol, UK Dr Wyatt is Director of Undergraduate Studies for the School of Chemistry at Bristol University and also Director of BRISTOL ChemLabS - a HEFCE Centre for Excellence in Teaching & Learning. He is co-author, with Warren, of Organic Synthesis: Strategy and Control.

Inhaltsangabe

1. Introduction: Planning Organic Syntheses.. 2. Synthons and Reagents: Aromatic Compounds. 3. Strategy I: The Order of Events. 4. One
Group C
X Disconnections. 5. Chemoselectivity. 6. Two
Group C
X Disconnections. 7. Strategy III. 8. Amine Synthesis. 9. Protecting Groups. 10. One Group C
C Disconnections I: Alcohols. 11. General Strategy A: Choosing Disconnections. 12. Stereoselectivity A. 13. One Group C
C Disconnections II: Carbonyl Compounds. 14. Regioselectivity. 15. Alkene Synthesis. 16. Strategy VII: Use of Acetylenes. 17. Diels
Alder. 18. Strategy VIII: Carbonyl Condensations. 19. 1,3
diCO Compounds. 20. Control in C=O Condensations. 21. 1,5
diCO Compounds. 22. Nitro Groups. 23. 1,2
diCO Compounds. 24. Radicals. 25. 1,4
diCO Compounds. 26. Reconnection. 27. 1,6
diCO Compounds. 28. Strategy of C=O Disconnections. 29. Saturated Heterocycles. 30. Cyclopropanes. 31. Rearrangements. 32. Four
Membered Rings. 33. Ketenes. 34. Five
Membered Rings. 35. Pericyclic Reactions. 36. Six
Membered Rings. 37. Strategy of Ring Synthesis. 38. Stereoselectivity B. 39. Aromatic Heterocycles. 40: Advanced Strategy.

Rezensionen

This is a book which will change the way you think about making molecules. (Chemistry World, July 2008)

The authors can be commended on producing a really useful and enjoyable new book on Organic Synthesis. (Reviews, June 2008)

"The authors have spent approximately ten years putting this excellent book together, and their hard work has paid off." (Journal of Chemical Education, May 2008)

"Of interest to the experienced practitioner looking to broaden (or reawaken) awareness of the remarkable diversity of available synthetic transformations"(Journal of Medicinal Chemistry, 2008)