Paul Wyatt, Stuart Warren

Organic Synthesis (eBook, PDF)

Strategy and Control

• Format: PDF

Produktbeschreibung

Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 918
• Erscheinungstermin: 30. April 2007
• Englisch
• ISBN-13: 9780470061206
• Artikelnr.: 37289939

Autorenporträt

Paul Wyatt, Senior Lecturer and Director of Undergraduate Studies, School of Chemistry, University of Bristol, UK and Stuart Warren, Reader in Organic Chemistry, Department of Chemistry, University of Cambridge, UK.

Inhaltsangabe

1. Introduction: Planning Organic Syntheses.. 2. Synthons and Reagents: Aromatic Compounds. 3. Strategy I: The Order of Events. 4. One
Group C
X Disconnections. 5. Chemoselectivity. 6. Two
Group C
X Disconnections. 7. Strategy III. 8. Amine Synthesis. 9. Protecting Groups. 10. One Group C
C Disconnections I: Alcohols. 11. General Strategy A: Choosing Disconnections. 12. Stereoselectivity A. 13. One Group C
C Disconnections II: Carbonyl Compounds. 14. Regioselectivity. 15. Alkene Synthesis. 16. Strategy VII: Use of Acetylenes. 17. Diels
Alder. 18. Strategy VIII: Carbonyl Condensations. 19. 1,3
diCO Compounds. 20. Control in C=O Condensations. 21. 1,5
diCO Compounds. 22. Nitro Groups. 23. 1,2
diCO Compounds. 24. Radicals. 25. 1,4
diCO Compounds. 26. Reconnection. 27. 1,6
diCO Compounds. 28. Strategy of C=O Disconnections. 29. Saturated Heterocycles. 30. Cyclopropanes. 31. Rearrangements. 32. Four
Membered Rings. 33. Ketenes. 34. Five
Membered Rings. 35. Pericyclic Reactions. 36. Six
Membered Rings. 37. Strategy of Ring Synthesis. 38. Stereoselectivity B. 39. Aromatic Heterocycles. 40: Advanced Strategy.

Rezensionen

This is a book which will change the way you think about making molecules. (Chemistry World, July 2008)

The authors can be commended on producing a really useful and enjoyable new book on Organic Synthesis. (Reviews, June 2008)

"The authors have spent approximately ten years putting this excellent book together, and their hard work has paid off." (Journal of Chemical Education, May 2008)

"Of interest to the experienced practitioner looking to broaden (or reawaken) awareness of the remarkable diversity of available synthetic transformations"(Journal of Medicinal Chemistry, 2008)