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This first edition book integrates knowledge from all disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. Nature's Versatile Engine, is an expose of up-to-date advances in muscle research from the molecular to the organismal, covering all levels of biological organization. While the main emphasis is on Drosophila melanogaster (as it is the organism most widely studied), other species of flying insects are also covered. Because of its multidisciplinary nature, the book should appeal to just about anyone with an interest in muscle biology or insect…mehr

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Produktbeschreibung
This first edition book integrates knowledge from all disciplines that study muscle function, from single molecule biophysics to flight aerodynamics. Nature's Versatile Engine, is an expose of up-to-date advances in muscle research from the molecular to the organismal, covering all levels of biological organization. While the main emphasis is on Drosophila melanogaster (as it is the organism most widely studied), other species of flying insects are also covered. Because of its multidisciplinary nature, the book should appeal to just about anyone with an interest in muscle biology or insect flight. TOC:A naturalist's view of insect flight muscle.- Biology of muscle contractility.- Flight muscle mechanics and stretch activation.- Genetics of Drosophila flight muscle function.- Ultrastructure of crossbridge patterns in Lethocerus.- Comparative physiology of insect flight muscle.- Myosin.- Paramyosin.- Novel myosin associated proteins.- Thick filament structure.- Actin and arthrin.- Troponin, tropomyosin and GST-2.- Thin filiament structure.- Z Bands and transverse cytoskeletal networks.- Connecting filament structure and mechanics.- Projectin.- Titin and kettin.- Association of metabolic enzymes with the myofibril.- Muscles in action: x-ray diffraction live!.- Muscle systems design and integration.- Biochemical mechanics of insect flight and vertebrate cardiac muscle.- Molecular assays for actomyosin interactions.- Isoform variations and flight performance.- Data mining and comparative genomics.- Mutational proteomics.

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  • Produktdetails
  • Verlag: Springer-Verlag GmbH
  • Seitenzahl: 288
  • Erscheinungstermin: 24. Juni 2007
  • Englisch
  • ISBN-13: 9780387312132
  • Artikelnr.: 37288067
Autorenporträt
Jim Vigoreaux, University of Vermont, Burlington, VT, USA
Inhaltsangabe
Experimental Insect Flight Systems: Historical Contributions.- The Contributions of Genetics to the Study of Insect Flight Muscle Function.- 3D Structure of Myosin Crossbridges in Insect Flight Muscle.- Comparative Physiology of Insect Flight Muscle.- Stretch Activation.- Components of the Myofibril.- Myosin.- Paramyosin and Miniparamyosin.- Novel Myosin Associated Proteins.- Structure of the Insect Thick Filaments.- Actin and Arthrin.- Troponin, Tropomyosin and GST-2.- The Thin Filament in Insect Flight Muscle.- The Insect Z-Band.- Projectin, the Elastic Protein of the C-Filaments.- Some Functions of Proteins from the Drosophila sallimus (sls) Gene.- Towards a Systems Level Analysis of Muscle.- Sustained High Power Performance.- X-Ray Diffraction of Indirect Flight Muscle from Drosophila in Vivo.- Functional and Ecological Effects of Isoform Variation in Insect Flight Muscle.- Muscle Systems Design and Integration.- Molecular Assays for Acto-Myosin Interactions.- Insect Flight Muscle Chemomechanics.- Mapping Myofibrillar Protein Interactions by Mutational Proteomics.