Advances in Enzymology and Related Areas of Molecular Biology - Toone, Eric J.
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Enzymes are the primary catalysts of life processes. This book covers the advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes.
Volume 75 in the classic series Advances in Enzymology and Related Areas of Molecular Biology explores the area of protein evolution. This volume considers mechanisms of protein evolution broadly, including the use of evolutionary archeology to trace protein evolution, the conservation of structure-rather than sequence-in protein…mehr

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Produktbeschreibung
Enzymes are the primary catalysts of life processes. This book covers the advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes.
Volume 75 in the classic series Advances in Enzymology and Related Areas of Molecular Biology explores the area of protein evolution. This volume considers mechanisms of protein evolution broadly, including the use of evolutionary archeology to trace protein evolution, the conservation of structure-rather than sequence-in protein evolution, and the use of directed evolution to create new enzyme activities.

Chapters include:
_ Molecular Paleoscience: Systems Biology from the Past
_ A Structure-Centric View of Protein Evolution, Design, and Adaptation
_ Mechanisms of Protein Evolution and Their Applications to Protein Engineering
_ Novel Enzymes Through Design and Evolution
Autorenporträt
ERIC J. TOONE is Professor of Chemistry and Professor of Biochemistry at Duke University in Durham, North Carolina.