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This book is written by experts in the field of hematopoietic stem cell biology and lymphocyte development in order to overview recent advances in the field. Prospective isolation of various progenitors and stem cells enables us to understand self-renewal mechanisms of stem cells as well as regulation of hematopoiesis. Furthermore, the importance of extrinsic factors has been emphasized recently. This volume concisely describes our current understanding of normal hemato/lymphopoiesis as well as abnormal hematopoiesis, which may lead to leukemia.…mehr

Produktbeschreibung
This book is written by experts in the field of hematopoietic stem cell biology and lymphocyte development in order to overview recent advances in the field. Prospective isolation of various progenitors and stem cells enables us to understand self-renewal mechanisms of stem cells as well as regulation of hematopoiesis. Furthermore, the importance of extrinsic factors has been emphasized recently. This volume concisely describes our current understanding of normal hemato/lymphopoiesis as well as abnormal hematopoiesis, which may lead to leukemia.

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

  • Produktdetails
  • Verlag: Springer-Verlag GmbH
  • Erscheinungstermin: 4. Dezember 2009
  • Englisch
  • ISBN-13: 9781603273473
  • Artikelnr.: 37343037
Inhaltsangabe
List of Contributors
Acknowledgement
Preface
Chapter 1
Principles of hematopoietic Stem Cell Biology
Hideo Ema, Toshihiro Kobayashi, and Hiromitsu Nakauchi

Chapter 2
Hematopoietic Stem Cells and Their Niche
Hiroko Iwasaki and Toshio Suda

Chapter 3
Hematopoietic Stem Cells and Somatic Stem Cells
Kah Yong Tan, Francis S. Kim, Amy J. Wagers, and Shane R. Mayack
Chapter 4
Developmental Biology of Mammalian T cell progenitors: From Early Lymphoid Progenitors to Thymus-Colonizing Cells
Sophie Ezine, Laetitia Gautreau, Aude Parcelier and Bruno Canque

Chapter 5
GATA-1 and GATA-2 functions in hematopoietic differentiation
Takashi Moriguchi, Mikiko Suzuki, James Douglas Engel, and Masayuki Yamamoto

Chapter 6
Role of the IL-7 Receptor in T Cell Development from Hematopoietic Stem Cells
Koichi Ikuta and Shizue Tani-ichi

Chapter 7
Dendritic cell homeostasis - physiology and impact on disease
Miriam Merad and Markus G. Manz

Chapter 8
Wnt in hematopoietic and leukemic stem cells
Kim-Hien T. Dao and Catriona H. M. Jamieson
Rezensionen
From the reviews:
"The text is exceptionally well written by 23 contributors from Japan, the United States, France, and Switzerland-- all experts in their respective fields of hematopoietic stem cell biology and lymphocyte physiology. ... Hematopoietic Stem Cell Biology will be most helpful and interesting to readers wanting a current update of the field. It is well indexed and well referenced, although it includes few figures, schemas, or photographs to help elucidate the text." (Paulette Mehta, Journal of the American Medical Association, Vol. 304 (18), November, 2010)