Effect of some free radicals on biomolecules

Effect of some free radicals on biomolecules

Antioxidant and structure¿activity relationships (SARs)of some phenolic, anilines and heterocyclic compounds

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The scavenging behavior of a series of 36 phenolic, 17 anilines and 11 heterocyclic compounds toward Hydrogen peroxide and DPPH was examined.In Hydrogen peroxide scavenging activity, the aniline series are more active than the phenolic series due to the reduction properties of the aniline compounds. While, in the DPPH scavenging activity, the phenolic compounds are more active than the aniline compounds due to the lower bond dissociation energies (BDE) of O-H than that of N-H. The antioxidant activity related to the compound structure was found to be dependable on the number and position of th...