Structure-Activity Relationships for Development of Neurokinin-3 Receptor Antagonists (eBook, PDF)
Koki Yamamoto
eBook, PDF

Structure-Activity Relationships for Development of Neurokinin-3 Receptor Antagonists (eBook, PDF)

Reducing Environmental Impact

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This book explores the possible development of neurokinin-3 receptor (NK3R) antagonists with reduced environmental impact. Pharmaceuticals are used to cure diseases and to alleviate symptoms in humans and animals. However, the stable, bioactive substances excreted by patients have unfavorable effects on non-target species. To overcome these disadvantages of these highly stable, potent substances, drug design to turn off bioactivity after release into the environment is needed. The book describes the development of eco-friendly NK3R antagonists by introducing a labile functional moiety and subs...

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