Stereoselective Heterocycle Synthesis via Alkene Difunctionalization (eBook, PDF)

Stereoselective Heterocycle Synthesis via Alkene Difunctionalization (eBook, PDF)

Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation

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This book investigates the use of palladium modified by bulky ligands as catalysts for new chemical transformations that rapidly assemble several classes of complex heterocyles. It documents the development of new chemical reactions involving carbon-carbon (C¿C) and carbon-halogen (C¿X) bond formation in the context of alkene difunctionalization and dearomatization reactions. Due to the ubiquity of heterocycles in bioactive natural products and life-improving pharmaceutical treatments, a long-term goal for synthetic organic chemists has been to develop novel and creative heterocycle synthese...

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