Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials (eBook, ePUB)
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This book provides the application of generalized linear mixed-effects models and its related models in the statistical design and analysis of repeated measures adopted in randomized controlled trials. With increasing concerns about intra-patient variability of treatment effects, the traditional ANCOVA-type methods can no longer cope with these variability and the need for sophisticated methods for estimating treatment effects by taking intra-patient variability into account is immediate. The generalized linear mixedeffects model is one of such methods. The book emphasizes practical, rather th...
This book provides the application of generalized linear mixed-effects models and its related models in the statistical design and analysis of repeated measures adopted in randomized controlled trials. With increasing concerns about intra-patient variability of treatment effects, the traditional ANCOVA-type methods can no longer cope with these variability and the need for sophisticated methods for estimating treatment effects by taking intra-patient variability into account is immediate. The generalized linear mixedeffects model is one of such methods. The book emphasizes practical, rather than theoretical, aspects of mixed-effects models and interpretation of results.
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