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Peroxiporins (eBook, PDF)

Redox Signal Mediators In and Between Cells

Redaktion: Medraño-Fernandez, Iria; Sitia, Roberto; Bienert, Gerd Patrick
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To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Per...

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