Alfred Hassner, Irishi Namboothiri

Organic Syntheses Based on Name Reactions (eBook, ePUB)

A Practical Guide to Over 800 Transformations

• Format: ePub

Produktbeschreibung

Organic Syntheses Based on Named Reactions is an indispensable reference companion for chemistry students and researchers. Building on Hassner & Stumer's highly regarded 2e, this new work reviews 750 reactions, with over 100 new stereoselective and regioselective reactions. Each A-Z entry provides a carefully condensed summary of valuable information that a chemist needs to understand and utilize these fundamental reactions in their work, including brief practical details. The book is illustrated with real synthetic examples from the literature and about 3,400 references to the primary literature to aid further reading. Extensive indexes (name, reagent, reaction) and a very useful functional group transformation index help the reader fully navigate this extensive collection of important reactions. With its comprehensive coverage, superb organization and quality of presentation, this long-awaited new edition belongs on the shelf of every organic chemist.

• Handy reference guide that explains 750 established named processes and methods that are trusted and used by organic chemists to synthesize or transform molecules
• Provides key data on each transformation including background, mechanism and--uniquely to books in this area--experimental details
• Extensive and multiple indexes allow the reader to search for information as and how they want and to rapidly plan transformations

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 612
• Erscheinungstermin: 18. November 2011
• Englisch
• ISBN-13: 9780080966311
• Artikelnr.: 38125793

Autorenporträt

Alfred Hassner was born in 1930. He survived the holocaust as a young child. After WW II, he enrolled to the Technische Hochschule in Vienna (1949-1951), and then received his BSc from the University of Nebraska (1952). He obtained his PhD under Norman Cromwell at the University of Nebraska (1956) and then was a postdoc with Louis Fieser at Harvard University. He joined the University of Colorado at Boulder (1957) and became a Full Professor at the age of 36 (1966). In 1975, he moved to SUNY at Binghamton and in 1983 he joined Bar-Ilan University in Israel, where he was professor and after retirement Professor Emeritus, until his sad demise recently (2024) at the age of 94. Hassner mentored over 50 graduate students and more than 60 postdocs, published more than 320 research articles and 14 books and monographs, and has had a major impact on chemical science for the last 7 decades. Some of his most known contributions include the stereoselective introduction of nitrogen functionalities into organic molecules, the synthesis of steroidal heterocycles and other biologically active targets. He was one of the first to recognize the application of NMR half-widths to stereochemical structure assignments before high resolution NMR became available. Many useful reagents and concepts in organic synthesis are registered to his name. For example, he first proposed the concept of regiochemistry and regioselectivity, now universally used terminologies in organic chemistry. As a world-renowned expert in organic synthesis, he has held visiting professorships and appointments in many universities worldwide and also served as a valuable consultant for many industrial companies around the world. Hassner served as the president of the Israel Chemical Society - ICS (1991-1994). In 2007, he received the ICS prize for Excellence. In 2016, he received Honorary membership award for his lifetime achievement and outstanding contributions.Irishi N N Namboothiri was born in the southern Indian state Kerala in 1964. He received his MSc from Mangalore University (1988) and PhD from Indian Institute of Science, Bangalore (1994). He carried out postdoctoral research at Bar-Ilan University, Israel (1995-96), University of North Texas (1997-98) and Columbia University, USA (1999). After a brief stint as Senior Research Scientist at Sabinsa Corporation, New Jersey (2000), he joined the Department of Chemistry, Indian Institute of Technology (IIT) Bombay, Mumbai (2001) where he is currently a senior professor. His research interests include organic synthesis, development of new synthetic methodologies, asymmetric catalysis, mechanistic studies and materials chemistry. He is elected fellow of the Indian Academy of Sciences and National Academy of Sciences India. He is also a recipient of the Jean D'Alembert Senior Fellowship, Paris-Saclay University, France, Chemical Research Society of India Medal and Excellence in Teaching Award at IIT Bombay. He has supervised over 25 PhDs and co-authored nearly 200 publications (h-index 49) including four chapters and two books and is also a co-inventor of 6 patents. One of the books he co-authored is the third edition of "Organic Synthesis Based on Name Reactions with Alfred Hassner. Namboothiri has been a visiting professor at Alternative Energy and Atomic Energy Commission (CEA), Saclay, France and Federal University of Minas Gerais, Belo Horizonte, Brazil. He has delivered over 240 invited lectures at various symposia/conferences and special seminars in India and abroad. Currently, he is an Associate Editor of Journal of Chemical Sciences, Bangalore and is on the editorial board of Journal of Heterocyclic Chemistry. He also serves on several academic and research advisory committees in India.

Inhaltsangabe

Rearrangement
Reaction
Aromatic Tritylation
Ketone Oxidation
Arylpyridine synthesis
N-Heterocycle Amination
Indolizine Synthesis
Cyclohexene Synthesis
Reaction Asymmetric
Methylenation Reagent
Alkylation Acylation
Carbonylation
Reagents
Bromination
Grignard Reagent
Asymmetric Epoxidation
Allylation
Ce Reducing Agent
Aminomethylation
Addition
C-C Cross Coupling
Oxidation
Cyclopentenone
Annulation
Chromone
Quinoline
Oxazole
Asymmetric Epoxidation
C-C Coupling
Allylation; UGI Multicomponent Condensation
Reagent
Olefin Synthesis
Lactonization
Cyclohexadienone Synthesis

Rezensionen

"In this new edition the authors deliver a comprehensive guide to named reactions in organic synthesis. Woven between the classic named reactions which will be familiar to most readers are many which may not - over the course of the various editions, Hassner and colleagues have assigned names to a huge number of transformations which, whilst useful, were previously anonymous. Some may inevitably object to particular names being selected over others during this process; such is the nature of collaborative science. These concerns should, however, be pushed aside since what results is truly an invaluable resource, documenting genuinely useful reactions in an accessible and concise format. Readers familiar with one or both of the previous two editions will certainly want to investigate this latest version; the improvements go far beyond cosmetic changes and deliver an excellent reference text that would be an asset to libraries and bookshelves everywhere." --Chemistry World

"What sets this volume apart is the sheer number of reactions considered--750. In order to review that many reactions, Hassner (Bar-Ilan Univ., Israel) and Namboothiri (Indian Institute of Technology) can only provide a cursory examination of each reaction...The book is designed as a reference source, not a textbook. It seems like the type of resource that might be best moved online to take advantage of electronic search functions and ease in updating as more "name" reactions are developed. The volume's three separate indexes (by name, reagent, and reaction) facilitate finding information in the text. Summing Up: Recommended. Practicing synthetic organic chemists, including graduate students, researchers/faculty, and professionals." --CHOICE

"Organic chemists are in the habit of attaching a name (usually the name of the discoverer or those of the discoverers) to specific reactions or reagents. These "name reactions" help to convey information about specific trans- formations without the necessity to explain the finer details. The rapid expansion of the scientific literature has seen the number of name reactions grow enormously. Consequently, in the third edition of the book Organic Syntheses Based on Name Reactions A. Hassner and his coauthor I. Namboothiri have included as many as 750 named transformations. Despite the sheer number of transformations, which makes the book the most extensive of its kind, the authors have managed to limit the book to a compact size. A unique feature is the inclusion of a typical experimental procedure for every reaction, which is consistent with the subtitle "A practical guide. Clearly, the combination of a powerful index section, the experimental procedures, and the affordable price ensures a place for this book on the laboratory shelf of the practicing synthetic chemist as a quick and inspiring guide to modern organic chemistry." --Angewandte Books, 2012

"Hassner updates his reference to reactions known by the name of their discoverers with help from Namboothiri (chemistry, Indian Institute of Technology, Bombay). In response to comments, they have restored older named reactions cited in the 1994 first edition but not in the 2002 second; they have also added over 100 new reactions, and included recent references for others when available. The alphabetically arranged entries include descriptions, molecular diagrams, and the detailed procedure as well as a long list of references." --Reference and Research Book News, October 2012