One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B (eBook, ePUB)

• Format: ePub

Produktbeschreibung

One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B, Volume 369 provides in-depth reviews on the last progresses on the role of macrophages in health and diseases, with a special focus on the role of macrophages during development. New chapters cover The role of salivary gland macrophages in infection, disease and repair, Reprogramming or replacing brain macrophages to treat neurodegenerative disease, Targeting macrophages for cancer immunotherapy, Heart Macrophages at steady-state and disease: simple bystanders or active players?, Macrophages in the liver, and Developmental programming of macrophages.

• Provides accurate reviews from selected experts on the topic of macrophages in different tissues such as gut, kidney and heart
• Presents useful graphic material for ease of reading and learning for users
• Covers the latest insights and future perspectives on macrophage heterogeneity in different diseases

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 268
• Erscheinungstermin: 28. Mai 2022
• Englisch
• ISBN-13: 9780323907446
• Artikelnr.: 64109908

Autorenporträt

After defending an experimental thesis on malignant haematopoiesis, Samanta Mariani obtained a Master's Degree in Medical Biotechnology from the University of Modena and Reggio Emilia (Italy). She then moved to Milan to join an international PhD programme on Cellular and Molecular Biology held by the Vita-Salute San Raffaele University and the Open University of London.
During the four years of her PhD in Professor Guido Poli's laboratory, she worked on HIV-1 biology. After successfully defending her PhD thesis, she decided to move to the United States to experience a new research environment and broaden her scientific expertise. Changing scientific topics between the Master's and PhD led to her fascination in human haematopoiesis and the desire to find a postdoc in that field. Thus, she joined the laboratory of Professor Bruno Calabretta at the Thomas Jefferson University of Philadelphia. At the end of 2014, she joined Professor Elaine Dzierzak's laboratory for a second postdo

c at the University of Edinburgh. Here she worked on different projects focused on steady-state developmental haematopoiesis and immunology.
In 2021, she was awarded a Chancellor's Fellowship, a John Goldman Fellowship and entry to the ESAT tenure-track programme at the University of Edinburgh. This allowed her to open up a new line of research on embryonic macrophages and their role in health and disease, with a special focus on normal and malignant foetal/infant haematopoiesis.

Inhaltsangabe

1. The role of salivary gland macrophages in infection, disease and repair
John G. McKendrick and Elaine Emmerson
2. Mertk: An emerging target in cancer biology and immuno oncology
Kevin C. Lahey, Varsha Gadiyar, Amanda Hill, Samuel Desind, Ziren Wang, Viral Davra, Radhey Patel, Ahnaf Zaman, David Calianese and Raymond B. Birge
3. Targeting tumor-associated macrophages for cancer immunotherapy
Xu Cao, Seigmund W.T. Lai, Siqi Chen, Sadira Wang and Mingye Feng
4. Macrophages in the heart: Active players or simple bystanders?
Michele Bozzi, Valentina Parisi and Paolo Poggio
5. Macrophages as key regulators of liver health and disease
Eleni Papachristoforou and Prakash Ramachandran
6. Developmental programming of macrophages by early life adversity
Marlene S. Magalhaes, Harry G. Potter, Anna Ahlback and Rebecca Gentek