Non-coding RNAs in Complex Diseases (eBook, PDF)
eBook, PDF

Non-coding RNAs in Complex Diseases (eBook, PDF)

A Bioinformatics Perspective

Redaktion: Li, Xia; Zhang, Yunpeng; Ning, Shangwei; Xiao, Yun; Xu, Juan
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This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional prediction, to their roles in diseases. Computational methods used to investigate uncharacterised ncRNAs in diseases are mainly summarized in seven aspects: DNA variation of ncRNAs in diseases, prioritization of disease-related ncRNAs, dysregulation epigenetic factors that regulate ncRNA misexpression (DNA methylation and histone-modi...

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