eBook, PDF

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy (eBook, PDF)

Targeted Therapies to Reverse Resistance

Redaktion: Bonavida, Benjamin
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Patients with various cancers are treated with conventional chemotherapeutic drugs and the majority responds well to such therapies. However, there is a subset of patients who does not respond initially and another subset who no longer responds to further treatments. Clearly, in those two subsets of patients, the cancer cells exhibit mechanisms of resistance. One of the main challenges facing us to date is to develop new therapies to treat patients with the resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mech...

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