eBook, PDF

Medicinal Organometallic Chemistry (eBook, PDF)

Beschreibung

Contents: Gérard Jaouen, Nils Metzler-Nolte : Introduction ; Stéphane GIBAUD and Gérard JAOUEN: Arsenic - based drugs: from Fowler's solution to modern anticancer chemotherapy; Ana M. Pizarro, Abraha Habtemariam and Peter J. Sadler : Activation Mechanisms for Organometallic Anticancer Complexes; Angela Casini, Christian G. Hartinger, Alexey A. Nazarov, Paul J. Dyson : Organometallic antitumour agents with alternative modes of action; Elizabeth A. Hillard, Anne Vessières, Gerard Jaouen : Ferrocene functionalized endocrine modulators for the treatment of cancer; Megan Hogan and Matthias Tacke : Titanocenes - Cytotoxic and Anti-Angiogenic Chemotherapy Against Advanced Renal-Cell Cancer; Seann P. Mulcahy and Eric Meggers : Organometallics as Structural Scaffolds for Enzyme Inhibitor Design; Christophe Biot and Daniel Dive : Bioorganometallic Chemistry and Malaria; Nils Metzler-Nolte : Biomedical applications of organometal-peptide conjugates; Roger Alberto : Organometallic Radiopharmaceuticals; Brian E. Mann : Carbon Monoxide - an essential signaling molecule.

Technische Details

• Geräte: PC
• ohne Kopierschutz
• Größe: 6.33MB

Barrierefreiheit

• Text-to-Speech

Autor

Nils Metzler-Nolte studied chemistry in Hamburg, Freiburg and Munich, Germany. In 1994 he received his PhD for his work on synthesis, reactivity and electronic structure of alkynylboranes. After his postdoc in the laboratory of professor Green at the University of Oxford, Metzler-Nolte went to the well known Max-Planck-Institute for Bioinorganic Chemistry where he became leader of the group for bio-organometallic chemistry. Since 2000 he is professor for bioinorganic chemistry and medicinal inorganic chemistry and vice dean at the University of Heidelberg. His research is aimed at linking organometallic compounds to amino acids, small peptides and DNA analogs, namely PNAs.

Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 294
• Erscheinungstermin: 10. September 2010
• Englisch
• ISBN-13: 9783642131851
• Artikelnr.: 43802738

Rezensionen

From the reviews:
"Edited by Gèrard Jaouen and Nils Metzler-Nolte, this book describes recent advances in the design, synthesis, mechanistic understanding and medical application of organometallic compounds. ... Overall this is an informative book and will be welcomed by those working in the field of inorganic medicinal chemistry." (Simon P. Fricker, Platinum Metals Reviews, Vol. 55 (4), October, 2011)