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Mechanical Production of Nanoparticles in Stirred Media Mills (eBook, PDF)

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Nanotechnology applications in the pharmaceutical, materials, and chemical industries has renewed interest in the use of wet grinding in stirred media mills for the production of nanoparticles with controlled microstructure. Quite recently it is possible to mill particles down to the size range of 10 nm. However, challenges arise in the production of sub-micron particles that are, in part, due to colloidal surface forces influencing slurry stability and rheology. In this work experiments are performed on a well characterized model system of monodisperse primary nanoparticles that are salt...

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