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Identification and Analysis of c-MYC-Interacting Proteins (eBook, PDF)

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Life of multicellular organisms depends on a balanced equilibrium of cellular growth, division, differentiation, and death. A large variety of mechanisms are in function to orchestrate these processes and assure permanent homeostasis. On the cellular level, progression through the cell cycle has to be tightly regulated in order to coordinate the interplay of growth and genome replication steps, which is monitored by different checkpoint pathways. In normal ontogenesis, a large number of proto-oncogenes fulfills essential functions for normal cell proliferation in response to extracellular sign...

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