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Human Health is a Matter of Timing: The Impact of Circadian Medicine on Disease and Health (eBook, PDF)

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Life on Earth is adapted to our planet's 24-hour rotation and orbital revolution around the sun. The circadian clock is an organism's natural timing device. It establishes a link between the organism and its external environment to drive rhythms in feeding, activity and rest, body temperature, and hormones, and it ranges from the level of the cell to the whole organism and from bacteria to mammals. The biological clock has emerged as a potent regulator of human physiology, and it orchestrates cellular trafficking to achieve whole-body metabolic synchronization. A temporary mismatch between thi...

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