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HCV Infection and Cryoglobulinemia (eBook, PDF)

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In 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These "cryoglobulins" were responsible for the corresponding clinical condition "cryoglobulinemia." Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia. Subsequent progress in this field was rather slow until the end of the 1980s, when cryoglobulinemia was definitively shown to be an extrahepatic manifestation of hepatitis C virus infection.The book is unique in its detailed presentation and fundamental approach. Highl...

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